Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   THITH_RS13575 Genome accession   NZ_CP007029
Coordinates   3042898..3044271 (+) Length   457 a.a.
NCBI ID   WP_006747275.1    Uniprot ID   W0DQE4
Organism   Thioalkalivibrio paradoxus ARh     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 3037898..3049271
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  THITH_RS13555 (THITH_14000) sucD 3038649..3039518 (-) 870 WP_006747279.1 succinate--CoA ligase subunit alpha -
  THITH_RS13560 (THITH_14005) sucC 3039515..3040675 (-) 1161 WP_006747278.1 ADP-forming succinate--CoA ligase subunit beta -
  THITH_RS13565 (THITH_14010) - 3040781..3041026 (+) 246 WP_025367575.1 PP0621 family protein -
  THITH_RS13570 (THITH_14015) - 3040989..3042671 (+) 1683 WP_006747276.1 PAS domain-containing sensor histidine kinase -
  THITH_RS13575 (THITH_14020) pilR 3042898..3044271 (+) 1374 WP_006747275.1 sigma-54 dependent transcriptional regulator Regulator
  THITH_RS13580 (THITH_14025) - 3044307..3044897 (-) 591 WP_006747274.1 nucleoside triphosphate pyrophosphatase -
  THITH_RS13585 (THITH_14030) rlmH 3044894..3045364 (-) 471 WP_006747273.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  THITH_RS13590 (THITH_14035) rsfS 3045396..3045782 (-) 387 WP_006747272.1 ribosome silencing factor -
  THITH_RS13595 (THITH_14040) nadD 3045798..3046442 (-) 645 WP_006747271.1 nicotinate-nucleotide adenylyltransferase -
  THITH_RS13600 (THITH_14045) - 3046522..3047760 (-) 1239 WP_232222309.1 glutamate-5-semialdehyde dehydrogenase -
  THITH_RS13605 (THITH_14050) holA 3047895..3048905 (-) 1011 WP_006747269.1 DNA polymerase III subunit delta -

Sequence

Protein


Download         Length: 457 a.a.        Molecular weight: 49987.42 Da        Isoelectric Point: 6.2009

>NTDB_id=116062 THITH_RS13575 WP_006747275.1 3042898..3044271(+) (pilR) [Thioalkalivibrio paradoxus ARh]
MSIKHVLVVDDEPDICELLEITLQRMGIETTTTTRMTRAVELLEGHRFDLCLTDMRMPDGDGLDLVRRIQDRCPELPVAI
ITAHGSIDTAVQALKLGAFDFVTKPVDLNLLRRLIDSALRLTESSGPEFAAESGSRAAGASPLLGNSPAMVQLRNRVARL
ARSQAPVIIVGESGSGKELVAREIHRLGPRADGPFIPVNCGAIPAELMESEFFGHRKGAFTGAVQTRVGLFREAHGGTLL
LDEVAELPLPLQVKLLRALQERAIKPVGASREEPVDVRILSATHRDLSADVAEGRFRQDLYYRLNVVELRVPPLRERYED
LEELTRHILARIAGQWGIPSLSLSDDALARLRQHPFPGNVRELENILERAAVMVDGPIIGCNALDFPDCSRAGTGPGGDP
AAIVEGRVALDDHLAEQERRALEAALAQTAGNRTAAARVLGLSFRQMRYRLKKLGID

Nucleotide


Download         Length: 1374 bp        

>NTDB_id=116062 THITH_RS13575 WP_006747275.1 3042898..3044271(+) (pilR) [Thioalkalivibrio paradoxus ARh]
ATGAGCATCAAGCATGTGCTGGTGGTGGATGACGAGCCCGATATCTGCGAACTGCTGGAGATCACGCTGCAGCGCATGGG
CATCGAGACCACCACCACGACACGCATGACGCGGGCGGTCGAGCTGCTGGAAGGGCACCGGTTCGACCTCTGCCTGACCG
ACATGCGCATGCCCGACGGCGATGGCCTGGATCTGGTCCGGCGGATCCAGGATCGTTGCCCGGAACTGCCCGTCGCGATC
ATCACGGCGCATGGGAGCATCGACACCGCAGTGCAGGCACTGAAACTCGGGGCCTTCGACTTCGTCACCAAGCCGGTCGA
CCTGAACCTGCTGCGCAGGCTCATCGATAGCGCGCTGCGCCTGACCGAAAGCAGCGGGCCGGAGTTTGCCGCAGAATCGG
GCTCACGCGCAGCGGGTGCGAGCCCGTTACTCGGGAATTCGCCCGCGATGGTTCAATTGCGTAACCGGGTGGCGCGCCTG
GCCCGCAGCCAGGCACCGGTGATCATCGTCGGCGAATCCGGCTCCGGCAAGGAGCTGGTGGCCCGCGAGATCCACCGCCT
GGGACCGCGGGCCGACGGGCCGTTCATCCCGGTCAACTGCGGCGCAATTCCGGCCGAGTTGATGGAGAGCGAGTTCTTCG
GCCACCGGAAGGGCGCCTTCACCGGCGCGGTCCAGACCCGGGTCGGCCTGTTCCGTGAGGCGCACGGCGGCACCCTGCTG
CTCGACGAGGTCGCCGAACTCCCGCTGCCGTTGCAGGTCAAGCTGCTGCGGGCCCTGCAGGAGCGGGCGATCAAGCCGGT
CGGCGCATCCCGCGAGGAACCGGTCGACGTACGCATCCTGTCGGCGACCCACCGCGACCTTTCCGCGGATGTCGCGGAGG
GGCGTTTCCGGCAGGATCTGTATTACCGGCTGAACGTGGTGGAACTGCGGGTTCCCCCGCTGCGCGAACGCTACGAGGAT
CTCGAGGAACTGACGCGGCACATTCTCGCGCGCATCGCCGGGCAGTGGGGTATCCCGAGCCTGTCGCTGTCCGACGATGC
ACTGGCCCGGCTCAGGCAGCACCCGTTTCCCGGCAACGTTCGCGAGTTGGAGAACATCCTCGAGCGCGCCGCGGTCATGG
TCGACGGGCCGATCATCGGCTGCAACGCGCTCGATTTTCCGGACTGTTCCAGAGCGGGAACCGGACCGGGGGGCGACCCG
GCCGCGATCGTGGAGGGCCGAGTGGCGCTGGACGATCACCTGGCCGAGCAGGAGCGCCGCGCACTGGAAGCCGCGCTGGC
GCAGACCGCGGGCAACCGCACTGCAGCCGCCCGCGTGCTGGGCCTGAGCTTCCGACAGATGCGCTATCGGCTGAAGAAGC
TGGGCATCGACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(6-115)

Bacterial regulatory protein, Fis family (HTH_8)

(414-454)

Sigma-54 interaction domain (Sigma54_activat)

(143-309)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W0DQE4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

58.643

100

0.586
  pilR Acinetobacter baumannii strain A118

47.323

100

0.484
  luxO Vibrio cholerae strain A1552

37.9

95.842

0.363

Multiple sequence alignment