Detailed information NTG1160216

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: QSK41_RS33020
• Genome accession: NZ_OX638701
• Coordinates: 7039332..7040669 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain 4782MK isolate 4782MK
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 7034332..7045669

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QSK41_RS32995 (PAER4782_32950)	pgeF	7034475..7035203 (-)	729	WP_003161770.1	peptidoglycan editing factor PgeF	-
QSK41_RS33000 (PAER4782_32955)	rluD	7035200..7036162 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
QSK41_RS33005 (PAER4782_32960)	-	7036308..7037333 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
QSK41_RS33010 (PAER4782_32965)	-	7037490..7037735 (+)	246	WP_003102591.1	PP0621 family protein	-
QSK41_RS33015 (PAER4782_32970)	pilS	7037725..7039317 (+)	1593	WP_003110428.1	two-component system sensor histidine kinase PilS	Regulator
QSK41_RS33020 (PAER4782_32975)	pilR	7039332..7040669 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
QSK41_RS33025 (PAER4782_32980)	thiO	7040715..7041809 (-)	1095	WP_023084775.1	glycine oxidase ThiO	-
QSK41_RS33030 (PAER4782_32985)	-	7041944..7042453 (+)	510	WP_003161431.1	Tfp pilus assembly protein FimT/FimU	-
QSK41_RS33035 (PAER4782_32990)	-	7042559..7043065 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
QSK41_RS33040 (PAER4782_32995)	pilV	7043056..7043613 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
QSK41_RS33045 (PAER4782_33000)	pilW	7043610..7044434 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
QSK41_RS33050 (PAER4782_33005)	pilX	7044431..7045018 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1160216 QSK41_RS33020 WP_003094694.1 7039332..7040669(+) (pilR) [Pseudomonas aeruginosa strain 4782MK isolate 4782MK]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1160216 QSK41_RS33020 WP_003094694.1 7039332..7040669(+) (pilR) [Pseudomonas aeruginosa strain 4782MK isolate 4782MK]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGTGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384