Detailed information NTG1160142

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: QRQ54_RS27145
• Genome accession: NZ_OX638564
• Coordinates: 5816401..5817738 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain 3796A isolate 3796A
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5811401..5822738

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QRQ54_RS27120 (PAE3796A_26960)	pgeF	5811544..5812272 (-)	729	WP_043096283.1	peptidoglycan editing factor PgeF	-
QRQ54_RS27125 (PAE3796A_26965)	rluD	5812269..5813231 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
QRQ54_RS27130 (PAE3796A_26970)	-	5813377..5814402 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
QRQ54_RS27135 (PAE3796A_26975)	-	5814559..5814804 (+)	246	WP_003102591.1	PP0621 family protein	-
QRQ54_RS27140 (PAE3796A_26980)	pilS	5814794..5816386 (+)	1593	WP_003110428.1	two-component system sensor histidine kinase PilS	Regulator
QRQ54_RS27145 (PAE3796A_26985)	pilR	5816401..5817738 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
QRQ54_RS27150 (PAE3796A_26990)	thiO	5817784..5818878 (-)	1095	WP_023084775.1	glycine oxidase ThiO	-
QRQ54_RS27155 (PAE3796A_26995)	-	5819013..5819522 (+)	510	WP_043096282.1	Tfp pilus assembly protein FimT/FimU	-
QRQ54_RS27160 (PAE3796A_27000)	-	5819628..5820134 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
QRQ54_RS27165 (PAE3796A_27005)	pilV	5820125..5820682 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
QRQ54_RS27170 (PAE3796A_27010)	pilW	5820679..5821503 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
QRQ54_RS27175 (PAE3796A_27015)	pilX	5821500..5822087 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1160142 QRQ54_RS27145 WP_003094694.1 5816401..5817738(+) (pilR) [Pseudomonas aeruginosa strain 3796A isolate 3796A]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1160142 QRQ54_RS27145 WP_003094694.1 5816401..5817738(+) (pilR) [Pseudomonas aeruginosa strain 3796A isolate 3796A]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGTGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384