Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OOL12_RS00460 Genome accession   NZ_OX344719
Coordinates   83593..84222 (+) Length   209 a.a.
NCBI ID   WP_264717416.1    Uniprot ID   -
Organism   Staphylococcus aureus strain ST20190863 isolate ST20190863     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 78593..89222
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OOL12_RS00435 - 78913..79899 (-) 987 WP_000999713.1 FUSC family protein -
  OOL12_RS00440 map 80486..81244 (+) 759 WP_000636142.1 type I methionyl aminopeptidase -
  OOL12_RS00445 - 81461..81847 (+) 387 WP_001110179.1 hypothetical protein -
  OOL12_RS00450 liaF 81862..82563 (+) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  OOL12_RS00455 vraS 82560..83603 (+) 1044 WP_001017131.1 sensor histidine kinase Regulator
  OOL12_RS00460 vraR 83593..84222 (+) 630 WP_264717416.1 two-component system response regulator VraR Regulator
  OOL12_RS00465 - 84338..85555 (-) 1218 WP_061732697.1 YihY/virulence factor BrkB family protein -
  OOL12_RS00470 - 85833..86108 (-) 276 WP_000428172.1 YtxH domain-containing protein -
  OOL12_RS00475 - 86115..86579 (-) 465 WP_000228666.1 low molecular weight protein-tyrosine-phosphatase -
  OOL12_RS00480 - 86726..86926 (+) 201 WP_000180461.1 DUF1128 family protein -
  OOL12_RS00485 - 86929..88185 (+) 1257 WP_001795438.1 aminopeptidase -
  OOL12_RS00490 - 88275..88805 (+) 531 WP_000184383.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23545.34 Da        Isoelectric Point: 5.6942

>NTDB_id=1154814 OOL12_RS00460 WP_264717416.1 83593..84222(+) (vraR) [Staphylococcus aureus strain ST20190863 isolate ST20190863]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVKDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1154814 OOL12_RS00460 WP_264717416.1 83593..84222(+) (vraR) [Staphylococcus aureus strain ST20190863 isolate ST20190863]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGATGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGAAAGATAGAACACAAGCTGTTATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

99.043

100

0.99
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373

Multiple sequence alignment