Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   RG25_RS20440 Genome accession   NZ_CP010117
Coordinates   3991306..3991938 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain C2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3986306..3996938
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RG25_RS20415 (RG25_19405) yhfG 3986438..3986605 (+) 168 WP_000736862.1 YhfG family protein -
  RG25_RS20420 (RG25_19410) fic 3986595..3987197 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  RG25_RS20425 (RG25_19415) pabA 3987229..3987792 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  RG25_RS20430 (RG25_19420) argD 3987878..3989098 (+) 1221 WP_000963784.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  RG25_RS20435 (RG25_19425) yhfK 3989165..3991255 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  RG25_RS20440 (RG25_19430) crp 3991306..3991938 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  RG25_RS20450 (RG25_19440) yhfA 3992240..3992644 (+) 405 WP_001148908.1 OsmC family protein -
  RG25_RS20455 (RG25_19445) prkB 3992699..3993568 (-) 870 WP_001274680.1 phosphoribulokinase -
  RG25_RS20460 (RG25_19450) yheU 3993622..3993840 (-) 219 WP_000907085.1 YheU family protein -
  RG25_RS20465 (RG25_19455) yheT 3993834..3994856 (-) 1023 WP_000057405.1 hydrolase -
  RG25_RS20470 (RG25_19460) yheS 3994856..3996769 (-) 1914 WP_000634810.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=115216 RG25_RS20440 WP_000242755.1 3991306..3991938(-) (crp) [Escherichia coli strain C2]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=115216 RG25_RS20440 WP_000242755.1 3991306..3991938(-) (crp) [Escherichia coli strain C2]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467