Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MD993_RS08965 Genome accession   NZ_OV648025
Coordinates   1896163..1896792 (-) Length   209 a.a.
NCBI ID   WP_000153529.1    Uniprot ID   A0A7U7PW36
Organism   Staphylococcus argenteus isolate 20S00001-1_long     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1891163..1901792
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MD993_RS08935 - 1891571..1892101 (-) 531 WP_000184380.1 acyl-CoA thioesterase -
  MD993_RS08940 - 1892193..1893440 (-) 1248 WP_000656301.1 aminopeptidase -
  MD993_RS08945 - 1893452..1893652 (-) 201 WP_000180459.1 DUF1128 family protein -
  MD993_RS08950 - 1893799..1894263 (+) 465 WP_000228669.1 low molecular weight protein-tyrosine-phosphatase -
  MD993_RS08955 - 1894270..1894545 (+) 276 WP_000428174.1 YtxH domain-containing protein -
  MD993_RS08960 - 1894824..1896047 (+) 1224 WP_000037065.1 YihY/virulence factor BrkB family protein -
  MD993_RS08965 vraR 1896163..1896792 (-) 630 WP_000153529.1 two-component system response regulator VraR Regulator
  MD993_RS08970 vraS 1896782..1897825 (-) 1044 WP_001017131.1 sensor histidine kinase Regulator
  MD993_RS08975 liaF 1897822..1898523 (-) 702 WP_031788217.1 cell wall-active antibiotics response protein LiaF -
  MD993_RS08980 - 1898538..1898924 (-) 387 WP_001110170.1 hypothetical protein -
  MD993_RS08985 map 1899145..1899903 (-) 759 WP_031788218.1 type I methionyl aminopeptidase -
  MD993_RS08990 - 1900434..1901420 (+) 987 WP_031788370.1 aromatic acid exporter family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23517.28 Da        Isoelectric Point: 5.3889

>NTDB_id=1151910 MD993_RS08965 WP_000153529.1 1896163..1896792(-) (vraR) [Staphylococcus argenteus isolate 20S00001-1_long]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSKGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1151910 MD993_RS08965 WP_000153529.1 1896163..1896792(-) (vraR) [Staphylococcus argenteus isolate 20S00001-1_long]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTAGGTGAGGGGGCTTCAGGTAAAGAAGCAATCGCTAAAGCCCATGAGCTAAAACCTGATTTGATTTTAA
TGGATTTGCTTATGGATGATATGGATGGTGTAGAAGCGACTACTCAAATTAAAAAAGATTTACCACAAATTAAAGTATTA
ATGCTAACAAGTTTTATTGAAGATAAAGAGGTATATCGTGCCTTAGATGCAGGTGTTGATAGCTATATTTTAAAAACAAC
GAGTGCAAAAGATATTGCTGATGCAGTTCGTAAAACATCTAAAGGTGAATCTGTATTTGAACCTGAAGTATTAGTAAAAA
TGCGTAACCGTATGAAAAAACGTGCTGAGTTATATGAAATGTTAACGGAACGTGAAATGGAAATATTATTATTAATTGCC
AAAGGTTATTCAAATCAAGAGATTGCAAGTGCATCTCATATTACAATTAAAACAGTTAAGACACATGTAAGTAATATTTT
AAGTAAGTTAGAAGTACAAGATAGAACACAAGCCGTTATTTATGCATTCCAACATAATTTAATTCAGTAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7PW36

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

99.043

100

0.99
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373

Multiple sequence alignment