Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   RC72_RS00350 Genome accession   NZ_CP010116
Coordinates   42112..42744 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain C1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 37112..47744
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RC72_RS00320 (RC72_00310) yheS 37275..39194 (+) 1920 WP_001551739.1 ABC transporter ATP-binding protein -
  RC72_RS00325 (RC72_00315) yheT 39194..40216 (+) 1023 WP_001551740.1 hydrolase -
  RC72_RS00330 (RC72_00320) yheU 40210..40428 (+) 219 WP_000907085.1 YheU family protein -
  RC72_RS00335 (RC72_00325) prkB 40482..41351 (+) 870 WP_001274680.1 phosphoribulokinase -
  RC72_RS00340 (RC72_00330) yhfA 41406..41810 (-) 405 WP_001148908.1 OsmC family protein -
  RC72_RS00350 (RC72_00340) crp 42112..42744 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  RC72_RS00355 (RC72_00345) yhfK 42795..44885 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  RC72_RS00360 (RC72_00350) argD 44948..46171 (-) 1224 WP_001551741.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  RC72_RS00365 (RC72_00355) pabA 46257..46820 (-) 564 WP_001551743.1 aminodeoxychorismate synthase component 2 -
  RC72_RS00370 (RC72_00360) fic 46852..47454 (-) 603 WP_001280645.1 putative adenosine monophosphate-protein transferase Fic -
  RC72_RS00375 (RC72_00365) yhfG 47444..47611 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=115077 RC72_RS00350 WP_000242755.1 42112..42744(+) (crp) [Escherichia coli strain C1]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=115077 RC72_RS00350 WP_000242755.1 42112..42744(+) (crp) [Escherichia coli strain C1]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGATGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467