Detailed information NTG0114870

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: V529_RS17235
• Genome accession: NZ_CP006890
• Coordinates: 3583475..3584638 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis SQR9
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3578475..3589638

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V529_RS17205 (V529_35270)	-	3578740..3579159 (-)	420	WP_038460041.1	TIGR03826 family flagellar region protein	-
V529_RS17210 (V529_35280)	comFC	3579233..3579922 (-)	690	WP_199910472.1	double zinc ribbon domain-containing protein	Machinery gene
V529_RS17215 (V529_35290)	-	3579928..3580212 (-)	285	WP_003151389.1	competence protein ComFB	-
V529_RS17220 (V529_35300)	comFA	3580270..3581655 (-)	1386	WP_038460045.1	DEAD/DEAH box helicase	Machinery gene
V529_RS17225 (V529_35310)	-	3581763..3582611 (-)	849	WP_003151387.1	DegV family protein	-
V529_RS17230 (V529_35320)	degU	3582709..3583398 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
V529_RS17235 (V529_35330)	degS	3583475..3584638 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
V529_RS17240 (V529_35340)	-	3584861..3585508 (+)	648	WP_007614107.1	YigZ family protein	-
V529_RS17245 (V529_35350)	-	3585513..3586733 (+)	1221	WP_038460047.1	LCP family protein	-
V529_RS17250 (V529_35360)	-	3586832..3587908 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
V529_RS17255 (V529_35370)	-	3588041..3589237 (-)	1197	WP_038460049.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=114870 V529_RS17235 WP_007407484.1 3583475..3584638(-) (degS) [Bacillus velezensis SQR9]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=114870 V529_RS17235 WP_007407484.1 3583475..3584638(-) (degS) [Bacillus velezensis SQR9]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCATGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGCGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTAGTCAGCCAAATAACCGTCGTTTTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGATGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951