Detailed information
Bioinformatically predicted
Overview
| Name | comFA | Type | Machinery gene |
| Locus tag | MFPB19_RS02685 | Genome accession | NZ_LT960784 |
| Coordinates | 541971..543308 (+) | Length | 445 a.a. |
| NCBI ID | WP_056948838.1 | Uniprot ID | A0AAX0VDK6 |
| Organism | Latilactobacillus sakei isolate MFPB19 | ||
| Function | ssDNA transport into the cell (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 522865..563767 | 541971..543308 | within | 0 |
Gene organization within MGE regions
Location: 522865..563767
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MFPB19_RS02605 (MFPB19_0542) | - | 524373..524810 (-) | 438 | WP_099713118.1 | GNAT family N-acetyltransferase | - |
| MFPB19_RS02610 (MFPB19_0543) | - | 524974..525951 (-) | 978 | WP_011374185.1 | GMP reductase | - |
| MFPB19_RS02615 (MFPB19_0544) | - | 526098..527051 (-) | 954 | WP_011374186.1 | magnesium transporter CorA family protein | - |
| MFPB19_RS02620 (MFPB19_0545) | - | 527140..527976 (+) | 837 | WP_016264719.1 | methyltransferase domain-containing protein | - |
| MFPB19_RS02625 (MFPB19_0546) | trmL | 528229..528738 (+) | 510 | WP_011374188.1 | tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL | - |
| MFPB19_RS02630 (MFPB19_0547) | - | 528750..529157 (+) | 408 | WP_011374189.1 | DUF1149 family protein | - |
| MFPB19_RS02635 (MFPB19_0548) | - | 529297..531666 (+) | 2370 | WP_011374190.1 | FtsK/SpoIIIE family DNA translocase | - |
| MFPB19_RS02640 (MFPB19_0549) | yfmF | 531864..533135 (+) | 1272 | WP_011374191.1 | EF-P 5-aminopentanol modification-associated protein YfmF | - |
| MFPB19_RS02645 (MFPB19_0550) | yfmH | 533125..534429 (+) | 1305 | WP_025016333.1 | EF-P 5-aminopentanol modification-associated protein YfmH | - |
| MFPB19_RS02650 (MFPB19_0551) | ymfI | 534429..535160 (+) | 732 | WP_099713117.1 | elongation factor P 5-aminopentanone reductase | - |
| MFPB19_RS02655 (MFPB19_0552) | - | 535242..536165 (+) | 924 | WP_011374194.1 | helix-turn-helix domain-containing protein | - |
| MFPB19_RS02660 (MFPB19_0553) | pgsA | 536191..536775 (+) | 585 | WP_011374195.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
| MFPB19_RS02665 (MFPB19_0554) | recA | 536958..538025 (+) | 1068 | WP_011374196.1 | recombinase RecA | Machinery gene |
| MFPB19_RS02670 (MFPB19_0555) | rny | 538412..539977 (+) | 1566 | WP_076632200.1 | ribonuclease Y | - |
| MFPB19_RS02675 (MFPB19_0556) | - | 540130..541218 (+) | 1089 | WP_056948881.1 | glycosyltransferase family 4 protein | - |
| MFPB19_RS02680 (MFPB19_0557) | - | 541244..541909 (-) | 666 | WP_056948841.1 | YigZ family protein | - |
| MFPB19_RS02685 (MFPB19_0558) | comFA | 541971..543308 (+) | 1338 | WP_056948838.1 | DEAD/DEAH box helicase | Machinery gene |
| MFPB19_RS02690 (MFPB19_0559) | comFC | 543284..543979 (+) | 696 | WP_147658291.1 | ComF family protein | Machinery gene |
| MFPB19_RS02695 (MFPB19_0560) | hpf | 544106..544651 (+) | 546 | WP_056948836.1 | ribosome hibernation-promoting factor, HPF/YfiA family | - |
| MFPB19_RS02700 (MFPB19_0561) | secA | 544900..547263 (+) | 2364 | WP_011374203.1 | preprotein translocase subunit SecA | - |
| MFPB19_RS02705 (MFPB19_0562) | prfB | 547333..548449 (+) | 1117 | WP_099049013.1 | peptide chain release factor 2 | - |
| MFPB19_RS02710 (MFPB19_0563) | ftsE | 548580..549266 (+) | 687 | WP_011374205.1 | cell division ATP-binding protein FtsE | - |
| MFPB19_RS02715 (MFPB19_0564) | ftsX | 549256..550143 (+) | 888 | WP_016264727.1 | permease-like cell division protein FtsX | - |
| MFPB19_RS02720 (MFPB19_0565) | - | 550337..551470 (+) | 1134 | WP_016264728.1 | PDZ domain-containing protein | - |
| MFPB19_RS02725 (MFPB19_0566) | - | 551490..552203 (+) | 714 | WP_099713116.1 | response regulator transcription factor | - |
| MFPB19_RS02730 (MFPB19_0567) | pnpS | 552190..553851 (+) | 1662 | WP_099713115.1 | two-component system histidine kinase PnpS | - |
| MFPB19_RS02735 (MFPB19_0568) | - | 553944..554804 (+) | 861 | WP_076632197.1 | phosphate ABC transporter substrate-binding protein PstS family protein | - |
| MFPB19_RS02740 (MFPB19_0569) | pstC | 554814..555737 (+) | 924 | WP_011374211.1 | phosphate ABC transporter permease subunit PstC | - |
| MFPB19_RS02745 (MFPB19_0570) | pstA | 555737..556621 (+) | 885 | WP_016264731.1 | phosphate ABC transporter permease PstA | - |
| MFPB19_RS02750 (MFPB19_0571) | pstB | 556631..557440 (+) | 810 | WP_011374213.1 | phosphate ABC transporter ATP-binding protein PstB | - |
| MFPB19_RS02755 (MFPB19_0572) | pstB | 557461..558219 (+) | 759 | WP_011374214.1 | phosphate ABC transporter ATP-binding protein PstB | - |
| MFPB19_RS02760 (MFPB19_0573) | phoU | 558236..558913 (+) | 678 | WP_011374215.1 | phosphate signaling complex protein PhoU | - |
| MFPB19_RS02765 (MFPB19_0574) | - | 559143..559613 (+) | 471 | WP_056948830.1 | nucleoside 2-deoxyribosyltransferase | - |
| MFPB19_RS02770 (MFPB19_0575) | - | 559733..560599 (+) | 867 | Protein_524 | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | - |
| MFPB19_RS02775 (MFPB19_0576) | - | 560619..561566 (+) | 948 | WP_099713114.1 | L-threonine 3-dehydrogenase | - |
| MFPB19_RS02780 (MFPB19_0577) | liaX | 561753..563228 (+) | 1476 | WP_099712930.1 | daptomycin-sensing surface protein LiaX | - |
| MFPB19_RS02785 (MFPB19_0578) | - | 563256..563492 (+) | 237 | WP_099712931.1 | PspC domain-containing protein | - |
| MFPB19_RS02790 (MFPB19_0579) | - | 563492..563767 (+) | 276 | WP_099712932.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 445 a.a. Molecular weight: 50226.69 Da Isoelectric Point: 9.6659
>NTDB_id=1148422 MFPB19_RS02685 WP_056948838.1 541971..543308(+) (comFA) [Latilactobacillus sakei isolate MFPB19]
MGQPVIACGRQFTAAQLADTQNNNYSLPQIERRPAFLRVKQRLICQRCQQVVPSQTCLPDGRHYCAQCLLFGRLVEGDWL
YTIPEDHLFKTATPKLTWAGQLTVYQEQAAQAVVAVIQAHKWHVLTAVTGAGKTEMLFQGILVALQKGQRVCLAAPRVAV
CLELYPRLQAAFATTSIMLMHGEQTEPYRYTQLVICTTHQLLKFYHAFDTVIVDEVDAFPFVDNPVLATAVEQACKPQCA
LLYLTATPTPAIKRAIAAKQMTVSELPLRFHGGILPEPQRHVAFNWRPRLKKGRLPKRLEHDCQICLKNQQILLFVPQVR
LLKPVANRLSILLPAVRIETVHANDPEQIEKIAAFRAQQIQLMVTTTILERGVTFKNVAVLVLGAEHMVFNEAVLVQIAG
RAGRHKDYTQNPVHFYYQDYTRAIKGACRQIKAQNQRGWRLQSTV
MGQPVIACGRQFTAAQLADTQNNNYSLPQIERRPAFLRVKQRLICQRCQQVVPSQTCLPDGRHYCAQCLLFGRLVEGDWL
YTIPEDHLFKTATPKLTWAGQLTVYQEQAAQAVVAVIQAHKWHVLTAVTGAGKTEMLFQGILVALQKGQRVCLAAPRVAV
CLELYPRLQAAFATTSIMLMHGEQTEPYRYTQLVICTTHQLLKFYHAFDTVIVDEVDAFPFVDNPVLATAVEQACKPQCA
LLYLTATPTPAIKRAIAAKQMTVSELPLRFHGGILPEPQRHVAFNWRPRLKKGRLPKRLEHDCQICLKNQQILLFVPQVR
LLKPVANRLSILLPAVRIETVHANDPEQIEKIAAFRAQQIQLMVTTTILERGVTFKNVAVLVLGAEHMVFNEAVLVQIAG
RAGRHKDYTQNPVHFYYQDYTRAIKGACRQIKAQNQRGWRLQSTV
Nucleotide
Download Length: 1338 bp
>NTDB_id=1148422 MFPB19_RS02685 WP_056948838.1 541971..543308(+) (comFA) [Latilactobacillus sakei isolate MFPB19]
ATGGGACAACCAGTGATTGCCTGTGGCCGCCAGTTTACTGCGGCCCAGTTAGCCGATACGCAAAATAATAATTATAGTTT
ACCACAGATTGAGCGCCGACCCGCGTTTTTACGGGTCAAGCAACGTTTAATCTGCCAACGTTGTCAGCAAGTGGTACCGT
CGCAAACTTGCTTACCAGACGGCCGTCATTATTGCGCGCAGTGTTTGTTATTTGGTCGTTTAGTAGAAGGGGATTGGTTA
TATACAATCCCTGAGGATCATTTATTTAAAACCGCTACACCGAAGTTGACGTGGGCAGGCCAATTAACAGTGTATCAGGA
ACAAGCCGCCCAAGCAGTGGTAGCGGTTATTCAAGCCCATAAATGGCACGTATTAACAGCCGTGACCGGTGCCGGGAAGA
CCGAGATGCTTTTTCAAGGGATTCTAGTCGCACTACAAAAGGGACAGCGAGTGTGTTTGGCAGCACCTAGAGTCGCAGTT
TGTCTAGAACTGTATCCGCGCCTGCAAGCCGCCTTTGCGACGACTAGTATCATGTTGATGCATGGCGAGCAAACCGAGCC
CTATCGCTATACCCAGTTAGTGATTTGCACGACACATCAATTACTGAAGTTTTATCACGCTTTTGATACGGTCATCGTTG
ATGAAGTGGATGCTTTTCCTTTTGTTGATAATCCAGTTTTAGCCACGGCAGTTGAACAAGCCTGTAAGCCTCAGTGTGCG
TTATTATATTTAACGGCTACGCCGACACCAGCCATCAAGCGGGCGATTGCTGCTAAACAAATGACAGTTAGTGAATTACC
GCTTCGCTTTCATGGGGGAATATTGCCAGAACCGCAACGGCATGTCGCTTTCAATTGGCGGCCGCGATTAAAGAAGGGCC
GGTTACCTAAACGACTTGAGCATGATTGCCAGATTTGTTTAAAAAACCAGCAGATTTTGCTATTTGTACCGCAAGTCAGA
TTATTAAAACCAGTTGCCAATCGACTATCAATTTTATTACCGGCGGTCAGAATTGAGACGGTGCACGCAAACGATCCTGA
ACAAATTGAAAAGATCGCGGCGTTTAGGGCTCAACAAATTCAATTAATGGTGACGACCACTATTTTGGAGCGGGGGGTCA
CATTTAAAAATGTTGCGGTTTTGGTCTTAGGCGCGGAACACATGGTGTTTAATGAAGCCGTTTTGGTCCAGATTGCCGGG
CGAGCAGGACGGCATAAAGACTATACCCAAAATCCGGTTCATTTTTATTATCAGGATTATACCCGCGCTATTAAAGGAGC
TTGTCGGCAAATTAAGGCCCAAAATCAGAGGGGATGGCGATTACAATCAACTGTTTAA
ATGGGACAACCAGTGATTGCCTGTGGCCGCCAGTTTACTGCGGCCCAGTTAGCCGATACGCAAAATAATAATTATAGTTT
ACCACAGATTGAGCGCCGACCCGCGTTTTTACGGGTCAAGCAACGTTTAATCTGCCAACGTTGTCAGCAAGTGGTACCGT
CGCAAACTTGCTTACCAGACGGCCGTCATTATTGCGCGCAGTGTTTGTTATTTGGTCGTTTAGTAGAAGGGGATTGGTTA
TATACAATCCCTGAGGATCATTTATTTAAAACCGCTACACCGAAGTTGACGTGGGCAGGCCAATTAACAGTGTATCAGGA
ACAAGCCGCCCAAGCAGTGGTAGCGGTTATTCAAGCCCATAAATGGCACGTATTAACAGCCGTGACCGGTGCCGGGAAGA
CCGAGATGCTTTTTCAAGGGATTCTAGTCGCACTACAAAAGGGACAGCGAGTGTGTTTGGCAGCACCTAGAGTCGCAGTT
TGTCTAGAACTGTATCCGCGCCTGCAAGCCGCCTTTGCGACGACTAGTATCATGTTGATGCATGGCGAGCAAACCGAGCC
CTATCGCTATACCCAGTTAGTGATTTGCACGACACATCAATTACTGAAGTTTTATCACGCTTTTGATACGGTCATCGTTG
ATGAAGTGGATGCTTTTCCTTTTGTTGATAATCCAGTTTTAGCCACGGCAGTTGAACAAGCCTGTAAGCCTCAGTGTGCG
TTATTATATTTAACGGCTACGCCGACACCAGCCATCAAGCGGGCGATTGCTGCTAAACAAATGACAGTTAGTGAATTACC
GCTTCGCTTTCATGGGGGAATATTGCCAGAACCGCAACGGCATGTCGCTTTCAATTGGCGGCCGCGATTAAAGAAGGGCC
GGTTACCTAAACGACTTGAGCATGATTGCCAGATTTGTTTAAAAAACCAGCAGATTTTGCTATTTGTACCGCAAGTCAGA
TTATTAAAACCAGTTGCCAATCGACTATCAATTTTATTACCGGCGGTCAGAATTGAGACGGTGCACGCAAACGATCCTGA
ACAAATTGAAAAGATCGCGGCGTTTAGGGCTCAACAAATTCAATTAATGGTGACGACCACTATTTTGGAGCGGGGGGTCA
CATTTAAAAATGTTGCGGTTTTGGTCTTAGGCGCGGAACACATGGTGTTTAATGAAGCCGTTTTGGTCCAGATTGCCGGG
CGAGCAGGACGGCATAAAGACTATACCCAAAATCCGGTTCATTTTTATTATCAGGATTATACCCGCGCTATTAAAGGAGC
TTGTCGGCAAATTAAGGCCCAAAATCAGAGGGGATGGCGATTACAATCAACTGTTTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comFA | Latilactobacillus sakei subsp. sakei 23K |
91.685 |
100 |
0.917 |
| comFA/cflA | Streptococcus pneumoniae TIGR4 |
38.979 |
96.854 |
0.378 |
| comFA/cflA | Streptococcus pneumoniae Rx1 |
38.747 |
96.854 |
0.375 |
| comFA/cflA | Streptococcus pneumoniae D39 |
38.747 |
96.854 |
0.375 |
| comFA/cflA | Streptococcus pneumoniae R6 |
38.747 |
96.854 |
0.375 |
| comFA/cflA | Streptococcus mitis NCTC 12261 |
38.515 |
96.854 |
0.373 |
| comFA/cflA | Streptococcus mitis SK321 |
38.372 |
96.629 |
0.371 |