Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CKV93_RS07260 Genome accession   NZ_LT906464
Coordinates   1476134..1476763 (-) Length   209 a.a.
NCBI ID   WP_095117382.1    Uniprot ID   A0A240C5H4
Organism   Staphylococcus muscae strain NCTC13833     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1471134..1481763
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV93_RS07230 (SAMEA4412661_01479) - 1471444..1472682 (-) 1239 WP_095117376.1 aminopeptidase -
  CKV93_RS07235 (SAMEA4412661_01480) - 1472697..1472903 (-) 207 WP_095117377.1 DUF1128 family protein -
  CKV93_RS07240 (SAMEA4412661_01481) - 1473139..1473600 (+) 462 WP_095117378.1 low molecular weight protein-tyrosine-phosphatase -
  CKV93_RS07245 (SAMEA4412661_01482) - 1473600..1473890 (+) 291 WP_095117379.1 hypothetical protein -
  CKV93_RS07250 (SAMEA4412661_01483) - 1474100..1475362 (+) 1263 WP_095117380.1 YihY/virulence factor BrkB family protein -
  CKV93_RS07255 (SAMEA4412661_01484) - 1475510..1476079 (+) 570 WP_095117381.1 carbonic anhydrase -
  CKV93_RS07260 (SAMEA4412661_01485) vraR 1476134..1476763 (-) 630 WP_095117382.1 response regulator transcription factor Regulator
  CKV93_RS07265 (SAMEA4412661_01486) vraS 1476753..1477799 (-) 1047 WP_095117383.1 sensor histidine kinase Regulator
  CKV93_RS07270 (SAMEA4412661_01487) liaF 1477796..1478500 (-) 705 WP_095117384.1 cell wall-active antibiotics response protein LiaF -
  CKV93_RS07275 (SAMEA4412661_01488) - 1478513..1478902 (-) 390 WP_095117385.1 hypothetical protein -
  CKV93_RS07280 (SAMEA4412661_01489) map 1479001..1479762 (-) 762 WP_095117386.1 type I methionyl aminopeptidase -
  CKV93_RS07285 (SAMEA4412661_01490) - 1479857..1480855 (+) 999 WP_095117387.1 aromatic acid exporter family protein -
  CKV93_RS07290 (SAMEA4412661_01491) - 1480905..1481630 (-) 726 WP_095117388.1 type 1 glutamine amidotransferase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23308.85 Da        Isoelectric Point: 4.7737

>NTDB_id=1147751 CKV93_RS07260 WP_095117382.1 1476134..1476763(-) (vraR) [Staphylococcus muscae strain NCTC13833]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGGSGREAIEKAHELNPDVILMDLVMTDMDGVEATAQIKKDLPGIKVV
MLTSYIEDKEVYRALDAGVDSYILKTTSASDIASAIRKTNLGESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHGLIE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1147751 CKV93_RS07260 WP_095117382.1 1476134..1476763(-) (vraR) [Staphylococcus muscae strain NCTC13833]
ATGACGATTAAAGTGTTGTTTGTAGACGATCATGAGATGGTTCGGATTGGTATTTCGAGCTATCTTTCTACACAATCAGA
TATTGAAGTTGTAGGAGAAGGTGGATCGGGTAGAGAAGCGATTGAAAAAGCGCACGAATTAAATCCAGATGTAATTTTGA
TGGATCTAGTCATGACAGATATGGATGGTGTTGAAGCAACAGCACAAATTAAAAAAGATTTACCCGGGATTAAAGTAGTG
ATGCTGACGAGCTACATAGAGGATAAAGAGGTCTATCGTGCATTGGACGCTGGTGTGGACAGTTATATTCTGAAAACAAC
GAGTGCGAGTGACATTGCGTCTGCAATTCGTAAAACGAATCTCGGCGAGTCGGTATTCGAGGCGGAAGTATTAGTAAAAA
TGCGTAATCGTATGAAGCAACGTGCGGAGCTTTATGAAATGTTGACAGAACGAGAGATGGAAATATTATTGCTGATTGCA
AAAGGGTATTCTAACCAAGAGATTGCAAGTGCATCACATATTACAATCAAGACCGTTAAAACACATGTGAGTAACATATT
GAGTAAATTAGAAGTGCAAGATCGCACACAGGCAGTCATATATGCCTTCCAACATGGACTTATCGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A240C5H4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.431

100

0.904
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.378

Multiple sequence alignment