Detailed information NTG1147752

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CKV93_RS07265
• Genome accession: NZ_LT906464
• Coordinates: 1476753..1477799 (-)
• Length: 348 a.a.
• NCBI ID: WP_095117383.1
• Uniprot ID: A0A240C6C4
• Organism: Staphylococcus muscae strain NCTC13833
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1471753..1482799

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CKV93_RS07235 (SAMEA4412661_01480)	-	1472697..1472903 (-)	207	WP_095117377.1	DUF1128 family protein	-
CKV93_RS07240 (SAMEA4412661_01481)	-	1473139..1473600 (+)	462	WP_095117378.1	low molecular weight protein-tyrosine-phosphatase	-
CKV93_RS07245 (SAMEA4412661_01482)	-	1473600..1473890 (+)	291	WP_095117379.1	hypothetical protein	-
CKV93_RS07250 (SAMEA4412661_01483)	-	1474100..1475362 (+)	1263	WP_095117380.1	YihY/virulence factor BrkB family protein	-
CKV93_RS07255 (SAMEA4412661_01484)	-	1475510..1476079 (+)	570	WP_095117381.1	carbonic anhydrase	-
CKV93_RS07260 (SAMEA4412661_01485)	vraR	1476134..1476763 (-)	630	WP_095117382.1	response regulator transcription factor	Regulator
CKV93_RS07265 (SAMEA4412661_01486)	vraS	1476753..1477799 (-)	1047	WP_095117383.1	sensor histidine kinase	Regulator
CKV93_RS07270 (SAMEA4412661_01487)	liaF	1477796..1478500 (-)	705	WP_095117384.1	cell wall-active antibiotics response protein LiaF	-
CKV93_RS07275 (SAMEA4412661_01488)	-	1478513..1478902 (-)	390	WP_095117385.1	hypothetical protein	-
CKV93_RS07280 (SAMEA4412661_01489)	map	1479001..1479762 (-)	762	WP_095117386.1	type I methionyl aminopeptidase	-
CKV93_RS07285 (SAMEA4412661_01490)	-	1479857..1480855 (+)	999	WP_095117387.1	aromatic acid exporter family protein	-
CKV93_RS07290 (SAMEA4412661_01491)	-	1480905..1481630 (-)	726	WP_095117388.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40184.50 Da
• Isoelectric Point: 5.4392

>NTDB_id=1147752 CKV93_RS07265 WP_095117383.1 1476753..1477799(-) (vraS) [Staphylococcus muscae strain NCTC13833]
MNHYIRTIGSMLILVYAMFTVFFFIDKVFVNIIFFQGMLYKQIFGISVFLFINLVVVFFCILVGSVIAYKINQQYDWLQE
QIERAIQGETVGINDHQIELYNETIGLYQTLVPLNQELHKLRIKTQNLTNEQYNMNDLKVKKIIEDERQRLARELHDSVS
QQLFAASLMLSAIKETELEPPLDQQIPTLEKMIQESQLEMRALLLHLRPIGLKDKTLGEGIKSLVTDLQRKVPMKVIYDI
DTFEVPKGIEDHLFRITQEAISNTLRHANGTQVSVELLNRDGHLLLRIQDDGIGFNPDEKMEQSYGLKNMRERATEIGAT
FHIVSLPNAGTRIEVKAPLDKEGQQYDD

Nucleotide

• Length: 1047 bp

>NTDB_id=1147752 CKV93_RS07265 WP_095117383.1 1476753..1477799(-) (vraS) [Staphylococcus muscae strain NCTC13833]
ATGAATCATTATATCCGAACGATTGGTTCTATGTTGATATTAGTTTATGCAATGTTCACTGTGTTTTTCTTCATTGATAA
GGTATTTGTCAATATTATTTTTTTTCAAGGCATGTTGTATAAACAAATTTTCGGTATTTCAGTTTTTTTATTTATCAACT
TAGTTGTTGTATTTTTTTGTATTCTTGTCGGAAGTGTCATTGCGTATAAAATCAATCAACAATACGATTGGTTACAAGAA
CAAATTGAACGTGCTATACAAGGTGAGACAGTTGGTATTAATGATCATCAAATAGAACTATACAATGAAACGATTGGACT
TTATCAAACATTAGTTCCATTGAATCAAGAGTTGCATAAACTAAGAATTAAAACGCAGAATTTAACGAATGAACAGTATA
ATATGAATGACCTAAAGGTGAAAAAGATTATAGAAGATGAACGGCAACGTTTAGCACGTGAGCTACACGATAGTGTGTCT
CAACAGTTATTTGCGGCGAGTTTAATGTTGTCAGCGATTAAAGAGACAGAGTTGGAACCACCTTTAGATCAACAAATTCC
AACATTGGAGAAAATGATTCAAGAATCACAACTTGAGATGCGCGCATTGTTATTACACTTACGACCGATTGGTTTGAAAG
ATAAAACACTTGGAGAAGGAATCAAGTCACTAGTGACAGATTTGCAGCGCAAAGTACCGATGAAAGTTATTTATGACATC
GATACGTTTGAAGTGCCAAAGGGCATTGAAGATCATCTATTTCGTATTACTCAAGAAGCGATTTCTAATACATTAAGACA
TGCGAATGGGACACAAGTCAGTGTTGAGTTGTTGAATCGTGATGGACATCTTTTGTTGCGTATACAAGATGATGGCATCG
GATTTAACCCGGATGAAAAGATGGAACAGAGTTATGGATTAAAAAATATGAGAGAGCGTGCGACAGAGATTGGCGCAACG
TTCCATATCGTATCATTGCCGAATGCAGGAACGCGCATTGAGGTGAAAGCACCATTAGATAAGGAGGGTCAGCAGTATGA
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A240C6C4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	80.172	100	0.802