Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CKV88_RS08850 Genome accession   NZ_LT906460
Coordinates   1890888..1891517 (-) Length   209 a.a.
NCBI ID   WP_002464447.1    Uniprot ID   G5JJU2
Organism   Staphylococcus simiae strain NCTC13838     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1885888..1896517
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV88_RS08820 (SAMEA4384339_01798) - 1886214..1886744 (-) 531 WP_002464453.1 acyl-CoA thioesterase -
  CKV88_RS08825 (SAMEA4384339_01799) - 1886814..1888058 (-) 1245 WP_002464452.1 aminopeptidase -
  CKV88_RS08830 (SAMEA4384339_01800) - 1888073..1888273 (-) 201 WP_088177495.1 DUF1128 family protein -
  CKV88_RS08835 (SAMEA4384339_01801) - 1888420..1888884 (+) 465 WP_002464450.1 low molecular weight protein-tyrosine-phosphatase -
  CKV88_RS08840 (SAMEA4384339_01802) - 1888891..1889166 (+) 276 WP_002464449.1 hypothetical protein -
  CKV88_RS08845 (SAMEA4384339_01803) - 1889462..1890679 (+) 1218 WP_002464448.1 YihY/virulence factor BrkB family protein -
  CKV88_RS08850 (SAMEA4384339_01804) vraR 1890888..1891517 (-) 630 WP_002464447.1 two-component system response regulator VraR Regulator
  CKV88_RS08855 (SAMEA4384339_01805) vraS 1891507..1892550 (-) 1044 WP_002464446.1 sensor histidine kinase Regulator
  CKV88_RS08860 (SAMEA4384339_01806) liaF 1892547..1893248 (-) 702 WP_002464445.1 cell wall-active antibiotics response protein LiaF -
  CKV88_RS08865 (SAMEA4384339_01807) - 1893263..1893649 (-) 387 WP_002464444.1 hypothetical protein -
  CKV88_RS08870 (SAMEA4384339_01808) map 1893886..1894641 (-) 756 WP_002464443.1 type I methionyl aminopeptidase -
  CKV88_RS08875 (SAMEA4384339_01809) - 1894818..1895804 (+) 987 WP_002464442.1 aromatic acid exporter family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23620.19 Da        Isoelectric Point: 4.8783

>NTDB_id=1147649 CKV88_RS08850 WP_002464447.1 1890888..1891517(-) (vraR) [Staphylococcus simiae strain NCTC13838]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGESGKDAISKAHDLNPDLILMDLLMEDMDGVEATTQIKKDLPHIKVL
MLTSFIEDNEVYRALDAGVDSYILKTTSAKDIADAVRKTYNGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1147649 CKV88_RS08850 WP_002464447.1 1890888..1891517(-) (vraR) [Staphylococcus simiae strain NCTC13838]
ATGACGATTAAAGTATTATTTGTGGATGATCATGAAATGGTTCGTATCGGTATTTCTAGTTATTTATCAACGCAAAGTGA
TATAGAAGTAGTAGGTGAGGGTGAATCAGGTAAGGATGCTATTTCAAAGGCACATGACTTAAACCCGGACTTAATTTTAA
TGGATTTATTAATGGAAGATATGGATGGCGTCGAAGCTACTACGCAAATAAAAAAAGATTTGCCACATATTAAAGTATTA
ATGCTAACAAGTTTTATTGAAGATAATGAGGTTTATCGTGCTTTGGATGCTGGTGTTGATAGTTATATTTTAAAAACAAC
AAGTGCCAAAGATATTGCTGATGCTGTACGCAAAACATATAATGGGGAATCTGTTTTTGAACCTGAAGTATTAGTGAAAA
TGCGTAATCGTATGAAAAAGCGTGCTGAATTATATGAAATGTTAACCGAACGTGAAATGGAAATATTATTACTCATTGCT
AAAGGTTATTCTAATCAGGAAATCGCTAGTGCATCACATATCACCATAAAAACAGTTAAAACGCATGTAAGTAACATATT
AAGTAAATTGGAAGTACAAGATAGAACACAAGCTGTTATCTATGCCTTCCAACACAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5JJU2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.694

100

0.957
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373

Multiple sequence alignment