Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   CKV88_RS02355 Genome accession   NZ_LT906460
Coordinates   541363..541917 (+) Length   184 a.a.
NCBI ID   WP_002465111.1    Uniprot ID   A9YUV3
Organism   Staphylococcus simiae strain NCTC13838     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 536363..546917
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV88_RS02330 (SAMEA4384339_00473) cysE 537567..538229 (+) 663 WP_197697105.1 serine O-acetyltransferase -
  CKV88_RS02335 (SAMEA4384339_00474) cysS 538213..539613 (+) 1401 WP_002465115.1 cysteine--tRNA ligase -
  CKV88_RS02340 (SAMEA4384339_00475) - 539606..540010 (+) 405 WP_002465114.1 Mini-ribonuclease 3 -
  CKV88_RS02345 (SAMEA4384339_00476) rlmB 540018..540764 (+) 747 WP_002465113.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  CKV88_RS02350 (SAMEA4384339_00477) - 540764..541288 (+) 525 WP_002465112.1 NYN domain-containing protein -
  CKV88_RS02355 (SAMEA4384339_00478) sigH 541363..541917 (+) 555 WP_002465111.1 sigma-70 family RNA polymerase sigma factor Regulator
  CKV88_RS02360 rpmG 542036..542179 (+) 144 WP_002465110.1 50S ribosomal protein L33 -
  CKV88_RS02365 (SAMEA4384339_00479) secE 542232..542414 (+) 183 WP_002465109.1 preprotein translocase subunit SecE -
  CKV88_RS02370 (SAMEA4384339_00480) nusG 542427..542975 (+) 549 WP_002465108.1 transcription termination/antitermination protein NusG -
  CKV88_RS02375 (SAMEA4384339_00481) rplK 543156..543578 (+) 423 WP_002465107.1 50S ribosomal protein L11 -
  CKV88_RS02380 (SAMEA4384339_00482) rplA 543782..544477 (+) 696 WP_002465106.1 50S ribosomal protein L1 -
  CKV88_RS02390 (SAMEA4384339_00484) rplJ 544744..545244 (+) 501 WP_002465105.1 50S ribosomal protein L10 -
  CKV88_RS02395 (SAMEA4384339_00485) rplL 545287..545655 (+) 369 WP_002465104.1 50S ribosomal protein L7/L12 -
  CKV88_RS02400 (SAMEA4384339_00486) - 545837..546445 (+) 609 WP_002465103.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 184 a.a.        Molecular weight: 22058.62 Da        Isoelectric Point: 9.4257

>NTDB_id=1147626 CKV88_RS02355 WP_002465111.1 541363..541917(+) (sigH) [Staphylococcus simiae strain NCTC13838]
MTNQYLNISNDKQQLDTSTHFNNLLQQLHPTIMSRIMKMRISDCDKEDLYQEVIIRIYKATKTFDFNGKQPFKHYVQCVI
SSVKYDYLRKYLAINRRTESLINEYKVKYSNHSLYKETELCCLYKMQLTELQGQFKYLSIFEKEVMTLVCQYYSPKEIAT
ILNVSDKKVYNAIQRSKQKIKVYC

Nucleotide


Download         Length: 555 bp        

>NTDB_id=1147626 CKV88_RS02355 WP_002465111.1 541363..541917(+) (sigH) [Staphylococcus simiae strain NCTC13838]
GTGACAAATCAATATTTAAATATCTCTAATGATAAACAGCAACTAGATACATCCACACACTTTAACAACTTATTACAACA
ATTGCATCCGACAATTATGAGTAGGATCATGAAGATGAGAATTAGTGATTGTGATAAAGAAGATTTATATCAAGAAGTAA
TTATTAGAATCTATAAAGCAACAAAGACATTTGATTTTAATGGTAAACAACCATTTAAACATTATGTACAATGTGTTATA
AGTTCAGTGAAATATGATTATTTACGTAAATATTTAGCAATCAATAGAAGGACTGAAAGCTTAATTAACGAATATAAAGT
GAAGTATAGTAATCATTCGCTATATAAAGAAACAGAATTATGTTGTCTTTACAAAATGCAATTAACAGAACTGCAAGGAC
AATTTAAATATTTAAGTATATTTGAAAAGGAAGTAATGACGCTAGTATGTCAATATTATAGCCCTAAAGAAATTGCTACA
ATACTCAATGTTAGTGATAAAAAAGTATACAATGCAATACAGAGAAGTAAACAAAAAATTAAAGTATATTGTTAA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(24-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A9YUV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

51.412

96.196

0.495
  sigH Staphylococcus aureus N315

53.374

88.587

0.473

Multiple sequence alignment