Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   CKW04_RS15360 Genome accession   NZ_LT906442
Coordinates   3330190..3330849 (-) Length   219 a.a.
NCBI ID   WP_058480023.1    Uniprot ID   A0A0W1AD18
Organism   Legionella waltersii strain NCTC13017     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3325190..3335849
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKW04_RS15350 (SAMEA4504053_03142) - 3325536..3328073 (+) 2538 WP_058480021.1 EAL domain-containing protein -
  CKW04_RS15355 (SAMEA4504053_03143) uvrC 3328263..3330128 (-) 1866 WP_058480022.1 excinuclease ABC subunit UvrC -
  CKW04_RS15360 (SAMEA4504053_03144) letA 3330190..3330849 (-) 660 WP_058480023.1 two-component system response regulator LetA Regulator
  CKW04_RS15365 (SAMEA4504053_03145) phhA 3330981..3331799 (-) 819 WP_058480024.1 phenylalanine 4-monooxygenase -
  CKW04_RS15370 (SAMEA4504053_03146) - 3332005..3333111 (+) 1107 WP_058480025.1 molybdopterin-binding protein -
  CKW04_RS15375 (SAMEA4504053_03147) cgtA 3333058..3334083 (-) 1026 WP_058480026.1 Obg family GTPase CgtA -
  CKW04_RS15380 (SAMEA4504053_03148) rpmA 3334181..3334459 (-) 279 WP_058480027.1 50S ribosomal protein L27 -
  CKW04_RS15385 (SAMEA4504053_03149) rplU 3334472..3334783 (-) 312 WP_058480028.1 50S ribosomal protein L21 -
  CKW04_RS15390 (SAMEA4504053_03150) - 3334994..3335659 (+) 666 WP_058480029.1 50S ribosomal protein L25/general stress protein Ctc -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24620.74 Da        Isoelectric Point: 6.3487

>NTDB_id=1147251 CKW04_RS15360 WP_058480023.1 3330190..3330849(-) (letA) [Legionella waltersii strain NCTC13017]
MIKVLIVDDHALVRMGIRRLLEDLSDVTVVADAESGEQALAFVKTHNPDVILLDMKMPGIDGWEVTRRLKKSNPHIKVIA
VTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSIQEPQNSPFDLLSEREMQVMLMI
TSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNNLIQEE

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1147251 CKW04_RS15360 WP_058480023.1 3330190..3330849(-) (letA) [Legionella waltersii strain NCTC13017]
TTGATTAAAGTACTCATTGTTGATGACCATGCATTGGTTCGAATGGGAATTCGACGATTGCTAGAAGATTTGTCAGATGT
TACTGTGGTTGCTGATGCCGAAAGCGGAGAGCAGGCATTGGCCTTTGTTAAGACACATAACCCTGACGTTATTTTATTAG
ATATGAAAATGCCTGGTATTGATGGCTGGGAAGTCACGCGTCGATTAAAAAAATCGAATCCACATATTAAAGTCATTGCG
GTAACCGCTATCTGCTCTGACCCTTTGCCTACAAGAGTGTTGCAGTTGGGGGCTATGGGATACCTTACTAAGGAATCAGG
CGCAGAAGAAATGGCTGCAGCAATTCGTAAGGTTGCCAAAGGAGAGAAGTATCTCAGTGCGGAAATCGCCCAAAAAATGG
CGATAAACAGTATCCAAGAACCACAAAATTCGCCATTTGATTTATTGTCTGAGCGAGAGATGCAAGTCATGTTGATGATC
ACCAGCGGCATGAATGTACAAGACATTGCCGACCGATTGTTTTTAAGCAGTAAAACCATCAACGGGTACCGTTACCGCAT
GTTTGAAAAATTGGGAATTAAAAACGATGTTGAATTAACTTATTTAGCGATGAAACATCGAATTATCGAACATCCCAACA
ATTTAATTCAAGAAGAATAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-203)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0W1AD18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

94.064

100

0.941
  letA Legionella pneumophila strain ERS1305867

94.064

100

0.941

Multiple sequence alignment