Detailed information NTG1146661

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: VCBK1071_RS05260
• Genome accession: NZ_LT897797
• Coordinates: 1099397..1101640 (+)
• Length: 747 a.a.
• NCBI ID: WP_269460106.1
• Uniprot ID: -
• Organism: Vibrio cholerae isolate Vibrio cholerae str. BC1071
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1094397..1106640

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VCBK1071_RS05235 (VCBK1071_01022)	-	1094860..1095435 (-)	576	WP_000999601.1	PilZ domain-containing protein	-
VCBK1071_RS05240 (VCBK1071_01023)	lolC	1095611..1096819 (+)	1209	WP_057562753.1	lipoprotein-releasing ABC transporter permease subunit LolC	-
VCBK1071_RS05245 (VCBK1071_01024)	lolD	1096812..1097498 (+)	687	WP_001061290.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
VCBK1071_RS05250 (VCBK1071_01025)	lolE	1097499..1098743 (+)	1245	WP_101410392.1	lipoprotein-releasing ABC transporter permease subunit LolE	-
VCBK1071_RS05255 (VCBK1071_01026)	-	1098858..1099388 (-)	531	WP_001881633.1	DUF2062 domain-containing protein	-
VCBK1071_RS05260 (VCBK1071_01027)	comEC	1099397..1101640 (+)	2244	WP_269460106.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
VCBK1071_RS05265 (VCBK1071_01028)	msbA	1101671..1103419 (+)	1749	WP_101410396.1	lipid A ABC transporter ATP-binding protein/permease MsbA	-
VCBK1071_RS05270 (VCBK1071_01029)	lpxK	1103422..1104429 (+)	1008	WP_057562814.1	tetraacyldisaccharide 4'-kinase	-
VCBK1071_RS05275 (VCBK1071_01030)	-	1104410..1104589 (+)	180	WP_000350068.1	Trm112 family protein	-
VCBK1071_RS05280 (VCBK1071_01031)	kdsB	1104589..1105347 (+)	759	WP_000011327.1	3-deoxy-manno-octulosonate cytidylyltransferase	-

Sequence

Protein

• Length: 747 a.a.
• Molecular weight: 84459.66 Da
• Isoelectric Point: 7.7612

>NTDB_id=1146661 VCBK1071_RS05260 WP_269460106.1 1099397..1101640(+) (comEC) [Vibrio cholerae isolate Vibrio cholerae str. BC1071]
MTLLSNYWSLISFSITVLSAPYWPWMPSWGWAWLCLIVMVLLGYHRVGRQFLGFVAAILTIVLQGNLIRDQSNVLYQAGP
DIIIKGRVDSFFTQTRYAYEGFVLIHEVNGQTLNKMTRPRIRLSAPLLLQPNDRVEFSVTLKPIVGRLNQTGFDLEAHYM
AQSVVARAVVKPDTAYQIVQESGIRSSLFFELEQLTHTSPYQGLILALTFGERKGIDEQEWQALRNSGLIHLVAISGLHI
GIAFSVGYFLGLGMMRLHAQLLWSPFVCGALLAVLYAWLAGFTLPTQRALIMCLLNVALIMLAFPLSALKRILLTLVAVL
LWSPFASLSNSFWMSFLAVAIVLYQLASQSQRQVWWKALLWAQVFLVCLMAPVTAYFFGGLSVTAVLYNLVFIPWFSLVI
VPALFLGLLLMVVWPSVAAAYWPWVDWTFLPLDWALQFADVGWWVVPSKVQGVVAASVAILLLYRFMSLKACSLLLGMIG
LWWWFPSLTPLWRMDVLDVGHGLAIVIEQDERAIVYDTGSSWPGGSYVQSVIEPILQQRGLRQVDGVILSHLDNDHAGDW
QGLAERWQPNWIRASQLGTEFMPCIRGESWQWQSLHFTVLWPPQAVSRAYNQHSCVIRMTDTQSNHSVLLSGDVTAMGEW
LLARDGAQLQSEVMIVPHHGSKTSSTAEFIAQVNPKLAIASVAKDNRWNLPNPQVVARYQAQQVEWLDTGHAGQISLFFY
LDQLDWFTQRSLGWQPWYRQMLRKGVE

Nucleotide

• Length: 2244 bp

>NTDB_id=1146661 VCBK1071_RS05260 WP_269460106.1 1099397..1101640(+) (comEC) [Vibrio cholerae isolate Vibrio cholerae str. BC1071]
ATGACTCTCTTGTCGAATTACTGGTCTCTCATTTCTTTTTCGATCACCGTGCTGTCTGCCCCTTATTGGCCTTGGATGCC
GAGTTGGGGCTGGGCTTGGTTATGCCTTATTGTTATGGTTTTGCTCGGTTATCACCGAGTTGGCCGTCAATTCCTTGGCT
TCGTGGCTGCCATACTAACCATTGTGCTACAGGGCAACCTTATACGAGATCAATCCAATGTGCTCTATCAAGCAGGGCCG
GATATTATCATAAAAGGCCGTGTTGACAGCTTTTTTACGCAAACTCGTTACGCTTATGAGGGTTTTGTCCTCATTCATGA
AGTGAATGGACAAACCTTGAACAAAATGACTCGCCCTCGCATACGTTTAAGTGCCCCTTTACTGTTACAACCCAATGACC
GCGTCGAATTTTCGGTAACTCTCAAGCCGATAGTAGGTCGACTCAACCAAACCGGCTTTGATTTAGAAGCGCATTACATG
GCGCAATCTGTCGTCGCACGGGCGGTCGTAAAACCTGACACCGCTTATCAAATTGTGCAAGAGAGTGGCATAAGGTCAAG
TTTGTTTTTTGAGCTGGAACAATTAACGCATACCAGCCCATACCAAGGATTGATCTTAGCCCTGACGTTTGGCGAGCGAA
AAGGTATTGATGAGCAAGAGTGGCAAGCCTTACGCAATAGTGGCTTAATTCATTTAGTGGCGATTTCGGGGCTGCACATT
GGTATCGCTTTTAGCGTGGGTTATTTTCTCGGGCTCGGCATGATGCGTCTTCATGCTCAGTTATTGTGGTCCCCTTTTGT
GTGTGGGGCTTTACTGGCGGTGCTCTACGCTTGGCTGGCTGGATTTACGTTGCCTACTCAGCGTGCATTGATTATGTGCT
TACTCAATGTGGCGTTGATCATGTTGGCTTTTCCTCTTTCCGCGCTCAAGCGGATTCTACTCACCTTAGTCGCGGTCTTG
CTTTGGTCGCCATTCGCCTCACTTTCAAACAGTTTCTGGATGTCGTTTTTGGCGGTCGCGATTGTTCTCTACCAATTAGC
CAGTCAAAGCCAGCGTCAGGTGTGGTGGAAAGCTCTGCTTTGGGCGCAGGTGTTCCTCGTCTGTTTAATGGCGCCGGTCA
CGGCCTATTTTTTCGGTGGCTTAAGCGTAACGGCAGTTCTGTACAATTTGGTGTTTATTCCTTGGTTTTCGTTGGTGATT
GTCCCAGCTTTGTTTTTGGGCCTACTACTCATGGTGGTATGGCCTAGTGTGGCCGCCGCTTACTGGCCTTGGGTGGATTG
GACGTTTTTACCGCTCGATTGGGCTTTGCAGTTTGCCGATGTAGGCTGGTGGGTGGTACCCAGCAAAGTACAAGGTGTAG
TCGCAGCGAGTGTGGCCATCCTCTTGCTTTATCGATTTATGAGCCTAAAAGCCTGCAGCTTATTATTGGGTATGATTGGC
TTATGGTGGTGGTTTCCCTCTCTCACTCCACTTTGGCGAATGGATGTGCTGGATGTTGGACATGGCTTGGCGATTGTGAT
TGAGCAAGATGAGCGAGCAATTGTCTACGATACAGGCAGCAGTTGGCCGGGAGGCAGCTATGTGCAAAGCGTGATTGAGC
CTATTCTCCAACAGCGAGGGCTACGCCAAGTCGATGGAGTGATTTTAAGTCATCTTGATAATGATCATGCGGGTGATTGG
CAAGGTTTAGCTGAGCGCTGGCAACCTAATTGGATTCGTGCCAGCCAACTCGGGACAGAGTTTATGCCTTGTATCCGTGG
TGAAAGCTGGCAGTGGCAATCTCTCCATTTTACGGTGTTATGGCCACCACAAGCGGTTAGCCGAGCGTACAACCAGCATT
CGTGTGTGATTCGTATGACCGATACTCAGTCTAACCATTCTGTACTGCTCTCCGGGGATGTCACAGCCATGGGGGAGTGG
CTGCTTGCTCGCGACGGAGCGCAACTGCAAAGTGAGGTGATGATCGTGCCGCACCACGGCAGTAAAACATCGTCCACCGC
AGAGTTTATTGCCCAAGTGAATCCCAAACTTGCGATTGCTTCTGTGGCGAAAGATAACCGCTGGAATTTGCCTAATCCGC
AAGTCGTGGCACGTTATCAAGCTCAGCAAGTTGAGTGGCTAGATACTGGACACGCTGGGCAAATTAGCCTCTTTTTCTAT
CTAGATCAGCTGGATTGGTTTACCCAGCGTAGCCTTGGCTGGCAGCCTTGGTATAGGCAGATGCTGCGTAAAGGAGTAGA
ATGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (21-173)

• Competence protein (Competence) (208-464)

• Metallo-beta-lactamase superfamily (Lactamase_B) (499-679)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Vibrio cholerae strain A1552	99.732	100	0.997
comEC	Vibrio parahaemolyticus RIMD 2210633	41.347	100	0.419
comEC	Vibrio campbellii strain DS40M4	41.09	100	0.414