Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   VCBK1071_RS01630 Genome accession   NZ_LT897797
Coordinates   342661..343293 (-) Length   210 a.a.
NCBI ID   WP_000242749.1    Uniprot ID   A0A6G8D3R0
Organism   Vibrio cholerae isolate Vibrio cholerae str. BC1071     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 337661..348293
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VCBK1071_RS01610 (VCBK1071_00311) - 337814..339025 (+) 1212 WP_101410087.1 aspartate aminotransferase family protein -
  VCBK1071_RS01615 (VCBK1071_00312) astA 339165..340184 (+) 1020 WP_002162681.1 arginine N-succinyltransferase -
  VCBK1071_RS01620 (VCBK1071_00313) astD 340194..341651 (+) 1458 WP_033931404.1 succinylglutamate-semialdehyde dehydrogenase -
  VCBK1071_RS01625 (VCBK1071_00314) - 341794..342585 (+) 792 WP_000189091.1 DUF1338 domain-containing protein -
  VCBK1071_RS01630 (VCBK1071_00315) crp 342661..343293 (-) 633 WP_000242749.1 cAMP-activated global transcriptional regulator CRP Regulator
  VCBK1071_RS01635 (VCBK1071_00316) - 343536..344405 (-) 870 WP_001274667.1 phosphoribulokinase -
  VCBK1071_RS01640 (VCBK1071_00317) - 344502..344711 (-) 210 WP_000586561.1 YheU family protein -
  VCBK1071_RS01645 (VCBK1071_00318) - 344824..345813 (-) 990 WP_000627575.1 hydrolase -
  VCBK1071_RS01650 (VCBK1071_00319) - 345810..346295 (-) 486 WP_001278734.1 TIGR02444 family protein -
  VCBK1071_RS01655 (VCBK1071_00320) - 346296..348212 (-) 1917 WP_033931403.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23635.45 Da        Isoelectric Point: 8.2784

>NTDB_id=1146652 VCBK1071_RS01630 WP_000242749.1 342661..343293(-) (crp) [Vibrio cholerae isolate Vibrio cholerae str. BC1071]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHAGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERTAWVRAKTPCEVAEISFKKFRQLIQVNPDILMRLSGQMARRLQVTSQKVGDLAFLDVTGRIAQTLLNLARQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEEQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=1146652 VCBK1071_RS01630 WP_000242749.1 342661..343293(-) (crp) [Vibrio cholerae isolate Vibrio cholerae str. BC1071]
ATGGTTCTAGGTAAACCTCAAACCGATCCAACACTAGAGTGGTTTCTTTCACATTGTCACATTCATAAGTACCCATCAAA
AAGCACGCTGATCCACGCGGGTGAGAAGGCGGAAACGCTGTACTACATCGTAAAAGGTTCAGTTGCGGTACTGATCAAAG
ATGAAGAAGGTAAAGAGATGATTCTCTCTTACCTGAACCAAGGTGATTTCATCGGTGAACTCGGCCTGTTTGAAGAAGGT
CAAGAGCGTACCGCTTGGGTTCGTGCCAAAACACCGTGTGAAGTGGCTGAAATCTCATTTAAGAAATTCCGTCAGTTAAT
CCAAGTTAACCCAGACATTTTGATGCGCCTTTCAGGTCAAATGGCTCGTCGTCTGCAAGTGACCAGCCAGAAAGTTGGCG
ACCTTGCGTTCCTAGACGTAACTGGCCGTATCGCACAGACTCTGCTGAATCTTGCACGTCAGCCAGATGCGATGACTCAC
CCTGATGGTATGCAAATCAAGATCACTCGCCAAGAGATCGGTCAAATTGTTGGCTGTTCTCGCGAAACCGTTGGCCGCAT
CCTGAAGATGCTGGAAGAGCAGAACCTGATCTCTGCCCACGGTAAAACCATCGTGGTTTATGGCACTCGCTAA

Domains

Predicted by InterproScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8D3R0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

100

100

1
  crp Haemophilus influenzae Rd KW20

75.49

97.143

0.733
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment