Detailed information NTG1146633

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: PANN_RS27320
• Genome accession: NZ_LT883143
• Coordinates: 5712264..5713601 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa C-NN2 isolate early isolate NN2 (clone C)
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5707264..5718601

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PANN_RS27295 (PANN_54740)	pgeF	5707407..5708135 (-)	729	WP_003102588.1	peptidoglycan editing factor PgeF	-
PANN_RS27300 (PANN_54750)	rluD	5708132..5709094 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
PANN_RS27305 (PANN_54760)	-	5709240..5710265 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
PANN_RS27310 (PANN_54770)	-	5710422..5710667 (+)	246	WP_009316269.1	PP0621 family protein	-
PANN_RS27315 (PANN_54780)	pilS	5710657..5712249 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator
PANN_RS27320 (PANN_54790)	pilR	5712264..5713601 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
PANN_RS27325 (PANN_54800)	thiO	5713647..5714741 (-)	1095	WP_023087807.1	glycine oxidase ThiO	-
PANN_RS27330 (PANN_54810)	-	5714876..5715385 (+)	510	WP_003102595.1	GspH/FimT family pseudopilin	-
PANN_RS27335 (PANN_54820)	-	5715491..5715997 (+)	507	WP_003102598.1	GspH/FimT family pseudopilin	-
PANN_RS27340 (PANN_54830)	pilV	5715988..5716545 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
PANN_RS27345 (PANN_54840)	pilW	5716542..5717366 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
PANN_RS27350 (PANN_54850)	pilX	5717363..5717950 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1146633 PANN_RS27320 WP_003094694.1 5712264..5713601(+) (pilR) [Pseudomonas aeruginosa C-NN2 isolate early isolate NN2 (clone C)]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1146633 PANN_RS27320 WP_003094694.1 5712264..5713601(+) (pilR) [Pseudomonas aeruginosa C-NN2 isolate early isolate NN2 (clone C)]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACTCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAAAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384