Detailed information NTG1146618

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: PANN_RS10585
• Genome accession: NZ_LT883143
• Coordinates: 2243281..2245506 (+)
• Length: 741 a.a.
• NCBI ID: WP_003113988.1
• Uniprot ID: Q9HZM0
• Organism: Pseudomonas aeruginosa C-NN2 isolate early isolate NN2 (clone C)
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2238281..2250506

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PANN_RS10560 (PANN_21050)	-	2238587..2239186 (-)	600	WP_003105196.1	PilZ domain-containing protein	-
PANN_RS10565 (PANN_21060)	-	2239289..2240539 (+)	1251	WP_003091170.1	lipoprotein-releasing ABC transporter permease subunit	-
PANN_RS10570 (PANN_21070)	lolD	2240532..2241215 (+)	684	WP_003091168.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
PANN_RS10575 (PANN_21080)	-	2241285..2242529 (+)	1245	WP_003113987.1	lipoprotein-releasing ABC transporter permease subunit	-
PANN_RS10580 (PANN_21090)	-	2242617..2243150 (-)	534	WP_003091165.1	DUF2062 domain-containing protein	-
PANN_RS10585 (PANN_21100)	comA	2243281..2245506 (+)	2226	WP_003113988.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
PANN_RS10590 (PANN_21110)	exbB	2245579..2246214 (+)	636	WP_003091163.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
PANN_RS10595 (PANN_21120)	-	2246211..2246651 (+)	441	WP_003091161.1	ExbD/TolR family protein	-
PANN_RS10600 (PANN_21130)	lpxK	2246651..2247649 (+)	999	WP_003091159.1	tetraacyldisaccharide 4'-kinase	-
PANN_RS10605 (PANN_21140)	-	2247687..2247872 (+)	186	WP_003091157.1	Trm112 family protein	-
PANN_RS10610 (PANN_21150)	kdsB	2247872..2248636 (+)	765	WP_003091155.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
PANN_RS10615 (PANN_21160)	-	2248636..2249100 (+)	465	WP_003106924.1	low molecular weight protein-tyrosine-phosphatase	-
PANN_RS10620 (PANN_21170)	murB	2249097..2250116 (+)	1020	WP_009876758.1	UDP-N-acetylmuramate dehydrogenase	-

Sequence

Protein

• Length: 741 a.a.
• Molecular weight: 79979.60 Da
• Isoelectric Point: 10.3506

>NTDB_id=1146618 PANN_RS10585 WP_003113988.1 2243281..2245506(+) (comA) [Pseudomonas aeruginosa C-NN2 isolate early isolate NN2 (clone C)]
MRLGLPALAAGLLALRFLAELPSVGWLLGMAAAGLLLLFGRLYWLGLFLLGFAWACGSAQVALDGRLAAELDGRTLWLEG
RVVDLPASGEGVTRFRLEEVSAARGVLLPERLRLSWRGAPPLMGGERWRLAVTLKRPRGLVNAAGFDYEAWLLAQRVGAV
GTVKAGQRLQPASGLDAWRDAWRQRLLAVDAQGRGAALAALVLGDGSGLSAAEWRMFQDTGTVHLMVISGSHISLLAGML
YGLVAALHRLGCWPRRLPWLPCACALGLLGAWSYGLMAGFEVPVRRACLMVSLALVWRLRFRHLGLLTPLLATLVLVLLV
EPLASLQAGFWLSFLAVALLLWLFAGRLGRWRWWAAWGRAQWGMALGLAMPLLALGLPLSLSGAPANLLAVPWIELLVVP
PALAGSLLLWVPGLGEGLLRAAGVSLDLLFRALGLLAGLAEAWQPPAAAAWSVALGMLGALCWLAPAGLPLRALGAALLL
PALLPSSPPVEWGRAEVRVLDVGQGLAVLVRTREHVLLYDSGARQGAFDMGERVVVPVLRSLDLRRLDGLLLSHADNDHA
GGAPTVASRFPPVWLVSGEPARLPSPLFADSCDERSWSWDGVVFEQWAWAQAGDSNDRSCVLRVEADGEVLLLTGDISRA
AEHAWLARQADPRVDWLLAPHHGSRSSSGVAFVLRTRPRHVLVSRGWRNAFGHPHGEVMERYARVAAQVHDTARDGALTF
LLGSRGGARRERDSAHFWREK

Nucleotide

• Length: 2226 bp

>NTDB_id=1146618 PANN_RS10585 WP_003113988.1 2243281..2245506(+) (comA) [Pseudomonas aeruginosa C-NN2 isolate early isolate NN2 (clone C)]
ATGCGCCTGGGATTGCCAGCCCTCGCCGCGGGGCTGCTGGCCCTGCGCTTCCTGGCGGAATTGCCGTCGGTCGGCTGGCT
GCTGGGCATGGCCGCCGCCGGACTGTTGCTGCTGTTCGGCCGGCTGTACTGGCTGGGGTTGTTCCTGCTCGGGTTCGCCT
GGGCCTGCGGCTCGGCGCAAGTCGCCCTGGACGGACGCCTGGCCGCCGAGCTGGATGGTCGCACCCTTTGGCTGGAGGGG
CGTGTGGTCGATCTGCCGGCGAGCGGCGAGGGCGTCACGCGCTTCCGGCTGGAGGAGGTCAGCGCTGCGCGGGGCGTGCT
TCTTCCCGAGCGTCTGCGCCTGAGCTGGCGCGGCGCGCCGCCGCTGATGGGCGGCGAACGCTGGCGCCTGGCGGTGACCC
TGAAACGCCCCCGCGGCCTGGTGAACGCGGCGGGTTTCGACTACGAGGCCTGGTTGTTGGCGCAGCGGGTCGGTGCTGTG
GGCACGGTGAAGGCGGGCCAGCGCCTGCAGCCGGCCAGCGGCCTGGATGCCTGGCGCGATGCCTGGCGGCAGCGCCTGCT
GGCGGTCGACGCACAGGGGCGCGGCGCCGCCCTGGCGGCGCTGGTGCTGGGGGATGGCTCGGGGTTGAGCGCGGCCGAGT
GGCGAATGTTCCAGGACACCGGCACCGTGCATCTGATGGTCATCTCCGGTTCGCATATCTCGTTGCTGGCGGGGATGCTC
TATGGCCTGGTGGCGGCCTTGCATCGCCTGGGCTGCTGGCCGCGGCGCCTGCCCTGGCTGCCCTGTGCCTGCGCCCTGGG
TTTGCTTGGTGCCTGGAGCTACGGGTTGATGGCGGGTTTCGAGGTCCCGGTGCGGCGCGCCTGCCTGATGGTCAGCCTGG
CGCTGGTCTGGCGCCTGCGTTTCCGCCACCTGGGCTTGCTGACCCCGCTGCTGGCAACGCTGGTGCTGGTCTTGCTGGTC
GAGCCGCTGGCCAGCCTGCAGGCGGGGTTCTGGCTGTCGTTCCTGGCGGTTGCCCTGCTGCTCTGGCTGTTCGCCGGGCG
CCTTGGGCGCTGGCGCTGGTGGGCGGCCTGGGGGCGGGCGCAGTGGGGGATGGCGCTGGGGCTGGCGATGCCGCTGCTGG
CGCTGGGCCTGCCGTTGAGCCTGAGCGGAGCGCCGGCCAACCTGCTGGCGGTGCCTTGGATCGAACTGCTGGTAGTGCCC
CCGGCCCTGGCGGGGAGCCTGCTGCTGTGGGTGCCCGGGCTGGGCGAGGGGCTGCTTCGCGCCGCTGGCGTTTCGCTGGA
CCTGCTGTTTCGTGCGCTTGGCCTGCTGGCGGGCCTGGCCGAGGCCTGGCAGCCACCCGCCGCAGCGGCCTGGAGCGTAG
CGCTGGGCATGCTCGGCGCGCTCTGCTGGCTGGCGCCGGCTGGCTTGCCGTTGCGTGCCCTCGGTGCCGCGTTGCTACTG
CCGGCATTGTTGCCGTCATCGCCGCCTGTCGAATGGGGGCGGGCGGAAGTGCGGGTGCTGGACGTCGGCCAGGGGCTGGC
CGTGCTGGTGCGTACCCGAGAGCATGTCTTGCTCTATGACAGCGGTGCGCGGCAGGGGGCGTTCGACATGGGTGAGCGGG
TGGTGGTGCCGGTGCTGCGCAGCCTGGACCTGCGGCGCCTGGACGGCCTGTTGCTGAGCCATGCCGACAACGACCATGCA
GGCGGTGCTCCTACGGTCGCTTCCCGATTCCCGCCGGTTTGGCTGGTCAGCGGCGAACCCGCGCGCCTGCCTTCGCCGTT
GTTCGCGGACAGCTGCGACGAGCGGAGCTGGTCCTGGGATGGCGTGGTTTTCGAACAGTGGGCATGGGCACAGGCCGGCG
ACAGCAACGACCGCTCCTGTGTGCTGAGGGTCGAGGCCGATGGCGAAGTCCTGCTGCTGACCGGGGACATCTCGCGTGCG
GCCGAGCATGCCTGGCTGGCGCGACAGGCCGATCCCCGGGTCGACTGGTTGCTGGCGCCGCATCATGGCAGCCGCAGTTC
CTCCGGAGTCGCCTTCGTGTTGCGTACGCGGCCTCGCCATGTGCTGGTCTCGCGAGGTTGGCGCAACGCCTTCGGCCATC
CCCATGGCGAAGTGATGGAGCGTTACGCGAGGGTCGCCGCGCAGGTCCACGACACGGCACGCGACGGTGCCCTGACGTTT
CTCCTCGGAAGCCGTGGCGGCGCACGCCGGGAGCGTGATTCGGCGCACTTCTGGCGGGAAAAATGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (21-168)

• Metallo-beta-lactamase superfamily (Lactamase_B) (501-666)

• Competence protein (Competence) (201-464)

3D structure

• AlphaFold DB: Q9HZM0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	58.807	97.301	0.572
comA	Ralstonia pseudosolanacearum GMI1000	35.611	100	0.366