Detailed information NTG1146039

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: EDCC5055_RS07860
• Genome accession: NZ_LT671859
• Coordinates: 1566336..1566833 (-)
• Length: 165 a.a.
• NCBI ID: WP_001789864.1
• Uniprot ID: -
• Organism: Staphylococcus aureus isolate Clinical isolate
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1561336..1571833

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EDCC5055_RS07835 (EDCC5055_01457)	gcvPB	1561498..1562970 (-)	1473	WP_000202189.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPB	-
EDCC5055_RS07840 (EDCC5055_01458)	gcvPA	1562963..1564309 (-)	1347	WP_000019687.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-
EDCC5055_RS07845 (EDCC5055_01459)	gcvT	1564329..1565420 (-)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-
EDCC5055_RS07850 (EDCC5055_01461)	-	1565579..1566103 (-)	525	WP_001015117.1	shikimate kinase	-
EDCC5055_RS07855	-	1566093..1566239 (-)	147	WP_001789879.1	hypothetical protein	-
EDCC5055_RS07860 (EDCC5055_01462)	comGF	1566336..1566833 (-)	498	WP_001789864.1	competence type IV pilus minor pilin ComGF	Machinery gene
EDCC5055_RS07865 (EDCC5055_01463)	comGE	1566751..1567050 (-)	300	WP_000844413.1	hypothetical protein	Machinery gene
EDCC5055_RS07870 (EDCC5055_01464)	comGD	1567037..1567483 (-)	447	WP_001790850.1	competence type IV pilus minor pilin ComGD	Machinery gene
EDCC5055_RS07875 (EDCC5055_01465)	comGC	1567461..1567772 (-)	312	WP_073546256.1	competence type IV pilus major pilin ComGC	Machinery gene
EDCC5055_RS07880 (EDCC5055_01466)	comGB	1567786..1568856 (-)	1071	WP_000775708.1	competence type IV pilus assembly protein ComGB	Machinery gene
EDCC5055_RS07885 (EDCC5055_01467)	comGA	1568828..1569802 (-)	975	WP_000697228.1	competence type IV pilus ATPase ComGA	Machinery gene
EDCC5055_RS07890 (EDCC5055_01468)	-	1569854..1570477 (-)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
EDCC5055_RS07895 (EDCC5055_01469)	-	1570474..1570803 (-)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
EDCC5055_RS07900 (EDCC5055_01470)	-	1570803..1571789 (-)	987	WP_000161314.1	ROK family glucokinase	-

Sequence

Protein

• Length: 165 a.a.
• Molecular weight: 19164.88 Da
• Isoelectric Point: 10.2192

>NTDB_id=1146039 EDCC5055_RS07860 WP_001789864.1 1566336..1566833(-) (comGF) [Staphylococcus aureus isolate Clinical isolate]
MILSKVTNKFVLFQKIPLLIKRHVYSINVKAFSLIEMLVAMMVISITLLIVPDLIRLSKTFLIESRDLTTVDFEFFSRDI
LDDFKGVDRNDIEIRQHRIILHKGEEMIEYKLINNKIIKVVNDRGNITMINNVTAFTANIYYKSIIKITITVKVGTNVQT
KTIYV

Nucleotide

• Length: 498 bp

>NTDB_id=1146039 EDCC5055_RS07860 WP_001789864.1 1566336..1566833(-) (comGF) [Staphylococcus aureus isolate Clinical isolate]
ATGATATTAAGCAAAGTGACCAACAAATTTGTGCTATTTCAAAAAATACCACTTCTTATCAAAAGACATGTATACAGTAT
TAATGTCAAAGCTTTTTCGCTCATTGAAATGTTAGTAGCGATGATGGTTATAAGTATAACTTTACTAATTGTTCCAGACT
TAATTAGACTTAGTAAAACTTTTCTAATTGAAAGTAGGGATTTAACAACTGTAGATTTCGAATTTTTCTCAAGAGATATT
CTAGATGATTTTAAAGGAGTAGATAGAAACGATATTGAAATTAGGCAACACCGTATCATTTTACATAAAGGTGAAGAAAT
GATCGAATACAAATTAATTAATAATAAAATTATTAAAGTTGTAAATGACAGAGGAAATATAACAATGATTAATAATGTTA
CAGCATTTACTGCAAATATCTACTATAAATCCATTATTAAAATAACGATAACAGTTAAAGTCGGTACAAATGTGCAGACT
AAAACTATTTATGTATAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (67-155)

• Prokaryotic N-terminal methylation motif (N_methyl) (28-51)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Staphylococcus aureus MW2	100	100	1
comGF	Staphylococcus aureus N315	96.364	100	0.964