Detailed information NTG1145082

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: STACADC2_RS03175
• Genome accession: NZ_LT604076
• Coordinates: 587317..588318 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain ACA-DC
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 582317..593318

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STACADC2_RS03155 (STACADC2_0569)	smpB	583422..583886 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
STACADC2_RS03160 (STACADC2_0570)	-	584040..585446 (+)	1407	WP_087009785.1	Cof-type HAD-IIB family hydrolase	-
STACADC2_RS03165 (STACADC2_0571)	-	585448..585813 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
STACADC2_RS03170 (STACADC2_0572)	-	585916..587001 (-)	1086	WP_011225703.1	M24 family metallopeptidase	-
STACADC2_RS03175 (STACADC2_0573)	ccpA	587317..588318 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
STACADC2_RS03180	-	588377..588574 (+)	198	WP_014608125.1	hypothetical protein	-
STACADC2_RS03185 (STACADC2_0574)	-	588680..589444 (+)	765	WP_087009786.1	MmcQ/YjbR family DNA-binding protein	-
STACADC2_RS03190 (STACADC2_0575)	-	589459..590574 (+)	1116	WP_002950249.1	glycerate kinase	-
STACADC2_RS03195 (STACADC2_0576)	-	590613..591068 (-)	456	WP_087009787.1	YueI family protein	-
STACADC2_RS03200 (STACADC2_0577)	eno	591276..592580 (+)	1305	WP_011225708.1	surface-displayed alpha-enolase	-
STACADC2_RS03205 (STACADC2_0578)	-	592734..592918 (-)	185	Protein_569	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=1145082 STACADC2_RS03175 WP_004197422.1 587317..588318(+) (ccpA) [Streptococcus thermophilus strain ACA-DC]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1145082 STACADC2_RS03175 WP_004197422.1 587317..588318(+) (ccpA) [Streptococcus thermophilus strain ACA-DC]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCTCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCGAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCTGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547