Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AC2117_RS12695 Genome accession   NZ_LS999521
Coordinates   2646126..2646833 (+) Length   235 a.a.
NCBI ID   WP_042897906.1    Uniprot ID   A0A446ZLE6
Organism   Acinetobacter calcoaceticus isolate Acinetobacter calcoaceticus str. 2117     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2641126..2651833
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AC2117_RS12680 (AC2117_02514) - 2643942..2644751 (+) 810 WP_133974538.1 M23 family metallopeptidase -
  AC2117_RS12685 (AC2117_02515) - 2644748..2645173 (-) 426 WP_133974540.1 GNAT family N-acetyltransferase -
  AC2117_RS12690 (AC2117_02516) - 2645264..2645686 (-) 423 WP_004793672.1 OsmC family protein -
  AC2117_RS19095 - 2645822..2645884 (-) 63 Protein_2469 hypothetical protein -
  AC2117_RS12695 (AC2117_02517) crp 2646126..2646833 (+) 708 WP_042897906.1 cAMP-activated global transcriptional regulator CRP Regulator
  AC2117_RS12700 (AC2117_02518) - 2646993..2648042 (+) 1050 WP_133974542.1 NADP(H)-dependent aldo-keto reductase -
  AC2117_RS12705 (AC2117_02519) - 2648097..2648876 (-) 780 WP_133974544.1 M48 family metallopeptidase -
  AC2117_RS12710 (AC2117_02520) - 2648993..2649310 (-) 318 WP_133974546.1 hypothetical protein -
  AC2117_RS12715 (AC2117_02521) - 2649433..2650752 (-) 1320 WP_133974548.1 adenylosuccinate synthase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26547.24 Da        Isoelectric Point: 4.6726

>NTDB_id=1143496 AC2117_RS12695 WP_042897906.1 2646126..2646833(+) (crp) [Acinetobacter calcoaceticus isolate Acinetobacter calcoaceticus str. 2117]
MTSNFSQLSTDALSPGQLPESVKALLKRAHINRYPKRTTIVDAGTESKSLYLILKGSVSIILREDDEREIVVAYLNPGDF
FGEMGLFEPNPQRTAEVRTRDVCEIAEISYDNFHELSKQYPDLSYAVFAQLVRRLKNTTRKMTDLAFIDVSGRIARCLID
LSSQPEAMILPNGRQIRITRQEIGRIVGCSREMVGRVLKTLEDQGMIQTDGKAILIFDVSLEEAPVTDEEFEDEE

Nucleotide


Download         Length: 708 bp        

>NTDB_id=1143496 AC2117_RS12695 WP_042897906.1 2646126..2646833(+) (crp) [Acinetobacter calcoaceticus isolate Acinetobacter calcoaceticus str. 2117]
ATGACTTCAAATTTTTCACAACTCAGCACAGATGCTTTATCCCCGGGGCAACTACCTGAATCCGTTAAAGCATTGTTAAA
ACGTGCTCACATCAACAGATATCCAAAACGAACCACAATTGTTGATGCAGGAACAGAGTCGAAATCTTTATATTTAATTT
TAAAAGGTTCAGTTTCAATTATTTTACGTGAAGATGATGAACGTGAAATTGTTGTTGCATATTTGAATCCGGGCGACTTC
TTTGGGGAAATGGGGCTTTTCGAACCGAACCCTCAACGTACAGCTGAAGTTCGTACTCGTGATGTCTGTGAAATTGCAGA
AATTTCTTATGACAACTTCCACGAACTTAGCAAACAATATCCAGACTTAAGTTATGCTGTTTTTGCACAGCTTGTTCGCC
GTCTAAAAAATACGACCCGTAAAATGACAGATCTTGCATTTATTGATGTGTCTGGGCGTATTGCGCGTTGTTTAATCGAT
CTCTCTTCACAGCCAGAAGCAATGATTTTGCCAAATGGTCGTCAAATTCGTATTACTCGTCAAGAAATTGGCCGTATTGT
AGGTTGTTCACGTGAGATGGTTGGCCGTGTACTCAAAACCTTAGAAGATCAAGGCATGATCCAGACAGATGGTAAAGCTA
TTCTTATTTTTGATGTTTCATTAGAAGAGGCACCTGTTACTGATGAAGAATTCGAAGATGAAGAATAA

Domains

Predicted by InterproScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(152-219)

Cyclic nucleotide-binding domain (cNMP_binding)

(33-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A446ZLE6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Acinetobacter baumannii D1279779

97.447

100

0.974
  crp Vibrio cholerae strain A1552

47.317

87.234

0.413
  crp Haemophilus influenzae Rd KW20

48.705

82.128

0.4

Multiple sequence alignment