Detailed information NTG1143392

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: PA5486_RS29045
• Genome accession: NZ_LS998783
• Coordinates: 5912157..5913494 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa isolate
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5907157..5918494

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PA5486_RS29020 (PA5486_05641)	pgeF	5907300..5908028 (-)	729	WP_003102588.1	peptidoglycan editing factor PgeF	-
PA5486_RS29025 (PA5486_05642)	rluD	5908025..5908987 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
PA5486_RS29030 (PA5486_05643)	-	5909133..5910158 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
PA5486_RS29035 (PA5486_05644)	-	5910315..5910560 (+)	246	WP_003102591.1	PP0621 family protein	-
PA5486_RS29040 (PA5486_05645)	pilS	5910550..5912142 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator
PA5486_RS29045 (PA5486_05646)	pilR	5912157..5913494 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
PA5486_RS29050 (PA5486_05647)	thiO	5913540..5914634 (-)	1095	WP_023089635.1	glycine oxidase ThiO	-
PA5486_RS29055 (PA5486_05648)	-	5914769..5915278 (+)	510	WP_003112829.1	GspH/FimT family pseudopilin	-
PA5486_RS29060 (PA5486_05649)	-	5915384..5915890 (+)	507	WP_003102598.1	GspH/FimT family pseudopilin	-
PA5486_RS29065 (PA5486_05650)	pilV	5915881..5916438 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
PA5486_RS29070 (PA5486_05651)	pilW	5916435..5917259 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
PA5486_RS29075 (PA5486_05652)	pilX	5917256..5917843 (+)	588	WP_015648054.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1143392 PA5486_RS29045 WP_003094694.1 5912157..5913494(+) (pilR) [Pseudomonas aeruginosa isolate]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1143392 PA5486_RS29045 WP_003094694.1 5912157..5913494(+) (pilR) [Pseudomonas aeruginosa isolate]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384