Detailed information NTG1142829

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQL26_RS02305
• Genome accession: NZ_LS483521
• Coordinates: 420490..421491 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC8316
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 415490..426491

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL26_RS02280 (NCTC8316_00448)	-	416164..416847 (-)	684	WP_023078761.1	DUF969 domain-containing protein	-
DQL26_RS02285 (NCTC8316_00449)	-	417058..417984 (-)	927	WP_047235928.1	glycosyltransferase family 2 protein	-
DQL26_RS02290 (NCTC8316_00450)	-	418129..418506 (-)	378	WP_002985686.1	VOC family protein	-
DQL26_RS02295 (NCTC8316_00451)	-	418517..419182 (-)	666	WP_111693052.1	NAD(P)H-dependent oxidoreductase	-
DQL26_RS02300 (NCTC8316_00452)	-	419231..420316 (-)	1086	WP_111693053.1	aminopeptidase P family protein	-
DQL26_RS02305 (NCTC8316_00453)	ccpA	420490..421491 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQL26_RS02310 (NCTC8316_00454)	-	421622..422620 (+)	999	WP_111693054.1	glycosyltransferase family 4 protein	-
DQL26_RS02315 (NCTC8316_00455)	-	422622..423956 (+)	1335	WP_111693055.1	glycosyltransferase family 4 protein	-
DQL26_RS02320 (NCTC8316_00457)	thrS	424378..426321 (+)	1944	WP_111693056.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1142829 DQL26_RS02305 WP_002985680.1 420490..421491(+) (ccpA) [Streptococcus pyogenes strain NCTC8316]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1142829 DQL26_RS02305 WP_002985680.1 420490..421491(+) (ccpA) [Streptococcus pyogenes strain NCTC8316]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559