Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DQL17_RS00185 Genome accession   NZ_LS483496
Coordinates   39658..40332 (-) Length   224 a.a.
NCBI ID   WP_032824524.1    Uniprot ID   A0A0K9L2I4
Organism   Haemophilus influenzae strain NCTC8455     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 34658..45332
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL17_RS00165 (NCTC8455_00031) hinT 36365..36715 (+) 351 WP_005651576.1 purine nucleoside phosphoramidase -
  DQL17_RS00170 (NCTC8455_00032) - 36715..37065 (+) 351 WP_032824530.1 YcfL family protein -
  DQL17_RS00175 (NCTC8455_00033) nagZ 37069..38121 (+) 1053 WP_050948671.1 beta-N-acetylhexosaminidase -
  DQL17_RS00180 (NCTC8455_00034) rlmC 38118..39305 (+) 1188 WP_111688717.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  DQL17_RS00185 (NCTC8455_00035) crp 39658..40332 (-) 675 WP_032824524.1 cAMP-activated global transcriptional regulator CRP Regulator
  DQL17_RS00190 (NCTC8455_00036) - 40317..40568 (-) 252 WP_032824522.1 YheU family protein -
  DQL17_RS00195 (NCTC8455_00037) slmA 40591..41247 (-) 657 WP_050948673.1 nucleoid occlusion factor SlmA -
  DQL17_RS00200 (NCTC8455_00038) dut 41251..41706 (-) 456 WP_044330861.1 dUTP diphosphatase -
  DQL17_RS00205 (NCTC8455_00039) coaBC 42396..43610 (-) 1215 WP_111688718.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  DQL17_RS00210 (NCTC8455_00040) radC 43773..44438 (+) 666 WP_050846688.1 RadC family protein -
  DQL17_RS00215 (NCTC8455_00041) rpmB 44652..44888 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  DQL17_RS00220 (NCTC8455_00042) rpmG 44900..45070 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25076.74 Da        Isoelectric Point: 6.6042

>NTDB_id=1142704 DQL17_RS00185 WP_032824524.1 39658..40332(-) (crp) [Haemophilus influenzae strain NCTC8455]
MSNELTEVDDVVTSPQEETTPNDPILDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVSNLAFLDVAGRIAQ
TLMNLAKQPDAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1142704 DQL17_RS00185 WP_032824524.1 39658..40332(-) (crp) [Haemophilus influenzae strain NCTC8455]
ATGTCAAATGAATTAACTGAAGTTGATGATGTTGTAACATCTCCGCAGGAAGAAACAACACCGAATGATCCCATTTTAGA
TTGGTTTCTTACCCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCACGCAGGGGAAGATGCGACTACGT
TGTATTATGTAATTAAAGGCTCTGTAATGGTGTCTTCAAAAGATGATGAAGGCAAAGAGATGATTCTCACTTACTTAGGT
GCAGGACAATTTTTTGGAGAAGCGGGATTATTTGATGAGGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAGATTTCTTATAAAAAATATCGTCAATTAATTCAAGCAAACCCAGAAATCTTAATGTTTTTAACCGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTAAGTAACCTTGCATTCTTAGATGTAGCAGGGCGTATCGCTCAA
ACACTGATGAATTTAGCTAAACAACCCGATGCAATGACCCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGGGAAACTGTGGGACGAATTATCAAGATGTTAGAGGATCAGAACCTTATTCATGCCC
ATGGAAAAACCATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K9L2I4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

95.982

100

0.96
  crp Vibrio cholerae strain A1552

73.364

95.536

0.701
  crp Acinetobacter baumannii D1279779

47.668

86.161

0.411

Multiple sequence alignment