Detailed information NTG1142176

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQN30_RS00040
• Genome accession: NZ_LS483458
• Coordinates: 8950..10071 (+)
• Length: 373 a.a.
• NCBI ID: WP_111697103.1
• Uniprot ID: A0A2X4UE11
• Organism: Haemophilus haemolyticus strain NCTC10839
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 3950..15071

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN30_RS00025 (NCTC10839_00005)	leuC	4214..5623 (-)	1410	WP_111695872.1	3-isopropylmalate dehydratase large subunit	-
DQN30_RS00030 (NCTC10839_00006)	leuB	5698..6774 (-)	1077	WP_111695873.1	3-isopropylmalate dehydrogenase	-
DQN30_RS00035 (NCTC10839_00007)	leuA	6859..8406 (-)	1548	WP_111695874.1	2-isopropylmalate synthase	-
DQN30_RS00040 (NCTC10839_00008)	dprA	8950..10071 (+)	1122	WP_111697103.1	DNA-processing protein DprA	Machinery gene
DQN30_RS00045 (NCTC10839_00009)	yaaA	10124..10900 (+)	777	WP_111695875.1	peroxide stress protein YaaA	-
DQN30_RS00050 (NCTC10839_00010)	-	10893..11474 (+)	582	WP_111695876.1	hypothetical protein	-
DQN30_RS00055 (NCTC10839_00011)	pfkA	11582..12547 (+)	966	WP_111695877.1	6-phosphofructokinase	-
DQN30_RS00060 (NCTC10839_00012)	smpB	12793..13275 (+)	483	WP_005633362.1	SsrA-binding protein SmpB	-
DQN30_RS00065 (NCTC10839_00013)	-	13327..14115 (-)	789	WP_005636887.1	outer membrane protein assembly factor BamD	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 41844.05 Da
• Isoelectric Point: 5.8720

>NTDB_id=1142176 DQN30_RS00040 WP_111697103.1 8950..10071(+) (dprA) [Haemophilus haemolyticus strain NCTC10839]
MHDITYTLLRLMQVPKLGGVGIDKILSNITLDELLNYDDVAFRQMGWGAIQIRRWFKPEAKFIEPALEWSQKEGNHLVNY
FSPFYPFLLKQIASFPPLLFVKGNLTALSQRQIAMVGSRYCTAYGEYWAKYFATELSLASFTITSGLALGIDGHCHQAVV
DIQGQTIAVLGSGLEQIYPVKHRKLSELILQNNGTLVSEFLPNQAPIATNFPRRNRIVSGLSVGTLVVEATEKSGSLITA
RYALEQNREVFAVPGNIQSEFSQGCNRLIKQGAMLVENAKDILETLYQHSIHSQTEIDFDQIAVPNYTPPPDPRRLVEAP
SHPKLYSRIGYTPVSIDDLAEEFNLSVDVLLVQLLDLELQDLIMSENGLYKRV

Nucleotide

• Length: 1122 bp

>NTDB_id=1142176 DQN30_RS00040 WP_111697103.1 8950..10071(+) (dprA) [Haemophilus haemolyticus strain NCTC10839]
ATGCACGATATTACTTATACGCTACTCCGCCTAATGCAAGTCCCTAAACTTGGCGGAGTGGGCATTGATAAAATTTTATC
CAATATTACGCTAGATGAGTTGCTCAATTATGATGATGTTGCTTTCCGACAAATGGGATGGGGCGCCATTCAAATTCGTC
GTTGGTTCAAGCCTGAAGCTAAATTTATTGAGCCAGCGCTAGAATGGTCACAAAAAGAGGGAAATCATTTAGTAAATTAT
TTTTCCCCTTTTTACCCCTTTCTATTGAAACAGATAGCAAGCTTTCCTCCTCTGTTATTTGTAAAAGGAAATTTGACCGC
ACTTTCACAACGTCAAATTGCGATGGTGGGAAGTCGCTACTGCACAGCTTATGGTGAATATTGGGCTAAATATTTTGCTA
CGGAACTTTCATTGGCTAGCTTTACGATTACTAGTGGACTCGCATTGGGAATAGATGGACATTGCCATCAAGCAGTTGTT
GATATTCAAGGACAAACGATAGCGGTTTTGGGAAGCGGGCTAGAACAAATTTATCCCGTAAAACACCGAAAACTTTCAGA
ACTTATTTTACAAAACAACGGTACATTAGTTTCTGAGTTTTTACCAAACCAAGCACCAATTGCGACAAATTTCCCTCGTC
GTAATAGGATTGTTAGCGGACTTTCTGTCGGGACATTAGTGGTTGAAGCCACAGAAAAAAGCGGCTCTCTGATTACCGCT
CGGTATGCATTGGAACAAAACCGAGAGGTTTTTGCTGTGCCAGGCAATATTCAAAGTGAATTTAGCCAAGGTTGTAATCG
CCTCATCAAACAAGGCGCAATGTTGGTGGAAAATGCAAAGGATATTTTGGAAACTCTCTACCAACATTCTATCCATAGCC
AAACTGAAATCGATTTTGACCAGATCGCTGTGCCTAATTACACGCCTCCACCCGATCCTCGGCGATTAGTAGAAGCACCA
AGTCACCCGAAACTTTATTCGCGTATCGGTTACACGCCTGTGAGCATTGATGATCTAGCTGAAGAATTTAACTTGAGTGT
CGATGTTTTACTTGTTCAGTTGCTCGATCTTGAATTGCAAGATCTCATCATGAGTGAAAATGGACTATATAAACGCGTTT
AG

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (71-277)

• DprA winged helix domain (DprA_WH) (311-367)

3D structure

• AlphaFold DB: A0A2X4UE11

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Haemophilus influenzae Rd KW20	93.566	100	0.936
dprA	Glaesserella parasuis strain SC1401	50.862	93.298	0.475
dprA	Vibrio campbellii strain DS40M4	43.207	98.66	0.426
dprA	Vibrio cholerae strain A1552	42.466	97.855	0.416