Detailed information NTG1142086

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQL01_RS10310
• Genome accession: NZ_LS483451
• Coordinates: 1921460..1922470 (-)
• Length: 336 a.a.
• NCBI ID: WP_111702731.1
• Uniprot ID: A0A4J2EMY9
• Organism: Streptococcus pneumoniae strain 4041STDY6836166
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1916460..1927470

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL01_RS10285	-	1917762..1918054 (-)	293	Protein_1947	hypothetical protein	-
DQL01_RS10290	-	1918216..1918668 (+)	453	WP_000079148.1	universal stress protein	-
DQL01_RS10295	-	1918703..1920091 (-)	1389	WP_000453139.1	Cof-type HAD-IIB family hydrolase	-
DQL01_RS10300	-	1920157..1921119 (+)	963	WP_111702729.1	asparaginase	-
DQL01_RS10305	-	1921148..1921396 (-)	249	WP_111702730.1	hypothetical protein	-
DQL01_RS10310	ccpA	1921460..1922470 (-)	1011	WP_111702731.1	catabolite control protein A	Regulator
DQL01_RS10315	-	1922894..1923493 (-)	600	WP_111702732.1	response regulator transcription factor	-
DQL01_RS10320	-	1923495..1924592 (-)	1098	WP_111702733.1	sensor histidine kinase	-
DQL01_RS10325	-	1924592..1925329 (-)	738	WP_000832843.1	ABC transporter permease	-
DQL01_RS10330	-	1925331..1926215 (-)	885	WP_111702734.1	ABC transporter ATP-binding protein	-
DQL01_RS10335	-	1926202..1926396 (-)	195	WP_061366326.1	hypothetical protein	-
DQL01_RS10340	-	1926393..1926599 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37087.04 Da
• Isoelectric Point: 5.3248

>NTDB_id=1142086 DQL01_RS10310 WP_111702731.1 1921460..1922470(-) (ccpA) [Streptococcus pneumoniae strain 4041STDY6836166]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIERLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=1142086 DQL01_RS10310 WP_111702731.1 1921460..1922470(-) (ccpA) [Streptococcus pneumoniae strain 4041STDY6836166]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGAACGCTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4J2EMY9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.405	100	0.994
ccpA	Streptococcus gordonii str. Challis substr. CH1	86.826	99.405	0.863
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568