Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   HPOKI422_RS00205 Genome accession   NZ_CP006824
Coordinates   37254..37997 (+) Length   247 a.a.
NCBI ID   WP_025275452.1    Uniprot ID   -
Organism   Helicobacter pylori oki422     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 32254..42997
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPOKI422_RS00180 (HPOKI422_00205) panD 34416..34766 (+) 351 WP_025276548.1 aspartate 1-decarboxylase -
  HPOKI422_RS00185 (HPOKI422_00210) - 34777..35070 (+) 294 WP_000347915.1 YbaB/EbfC family nucleoid-associated protein -
  HPOKI422_RS00190 (HPOKI422_00215) - 35070..36065 (+) 996 WP_025275450.1 PDZ domain-containing protein -
  HPOKI422_RS00195 (HPOKI422_00220) comB6 36073..37128 (+) 1056 WP_025366271.1 P-type conjugative transfer protein TrbL Machinery gene
  HPOKI422_RS00200 (HPOKI422_00225) comB7 37144..37257 (+) 114 WP_001217873.1 hypothetical protein Machinery gene
  HPOKI422_RS00205 (HPOKI422_00230) comB8 37254..37997 (+) 744 WP_025275452.1 type IV secretion system protein Machinery gene
  HPOKI422_RS00210 (HPOKI422_00235) comB9 37997..38992 (+) 996 WP_025366272.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HPOKI422_RS00215 (HPOKI422_00240) comB10 38985..40121 (+) 1137 WP_025276551.1 DNA type IV secretion system protein ComB10 Machinery gene
  HPOKI422_RS00220 (HPOKI422_00245) - 40191..41609 (+) 1419 WP_025276552.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HPOKI422_RS00225 (HPOKI422_00250) gmd 41619..42764 (+) 1146 WP_025275456.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28742.91 Da        Isoelectric Point: 8.9546

>NTDB_id=114206 HPOKI422_RS00205 WP_025275452.1 37254..37997(+) (comB8) [Helicobacter pylori oki422]
MKEKPFNSEQLNYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALILAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIALSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRND

Nucleotide


Download         Length: 744 bp        

>NTDB_id=114206 HPOKI422_RS00205 WP_025275452.1 37254..37997(+) (comB8) [Helicobacter pylori oki422]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGAACTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTCGGCTGGAAAGAAACCGCTTGAAAATCGCTT
ACAAGCTCTTAGGCTTGATGAGTTTTATCGCTCTTATTTTAGCGATCGTGTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACGCAAAACAGCATTTAT
GCGCAAAGCCATTTAGAAAGAGAGGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCTATTGCAGCTAAACTCATGAATGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGCACTGAGCTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACCCGCTACAGCATCACTGAAATC
GCGCCGACTAACAGGAATGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.761

100

0.968

Multiple sequence alignment