Detailed information NTG1142005

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQL12_RS10265
• Genome accession: NZ_LS483450
• Coordinates: 1892559..1893569 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 4041STDY6583227
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1887559..1898569

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL12_RS10240	-	1888679..1888973 (-)	295	Protein_1903	hypothetical protein	-
DQL12_RS10245	-	1889135..1889587 (+)	453	WP_000079148.1	universal stress protein	-
DQL12_RS10250	-	1889622..1891010 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
DQL12_RS10255	-	1891076..1892038 (+)	963	WP_050255554.1	asparaginase	-
DQL12_RS10260	-	1892067..1892495 (-)	429	WP_061745768.1	hypothetical protein	-
DQL12_RS10265	ccpA	1892559..1893569 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
DQL12_RS10270	-	1893994..1894593 (-)	600	WP_000866729.1	response regulator transcription factor	-
DQL12_RS10275	-	1894595..1895692 (-)	1098	WP_000893550.1	sensor histidine kinase	-
DQL12_RS10280	-	1895692..1896429 (-)	738	WP_000832826.1	ABC transporter permease	-
DQL12_RS10285	-	1896431..1897315 (-)	885	WP_000219354.1	ABC transporter ATP-binding protein	-
DQL12_RS10290	-	1897302..1897496 (-)	195	WP_000820185.1	hypothetical protein	-
DQL12_RS10295	-	1897493..1897699 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=1142005 DQL12_RS10265 WP_000990607.1 1892559..1893569(-) (ccpA) [Streptococcus pneumoniae strain 4041STDY6583227]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=1142005 DQL12_RS10265 WP_000990607.1 1892559..1893569(-) (ccpA) [Streptococcus pneumoniae strain 4041STDY6583227]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGCTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568