Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   ECONIH1_RS19655 Genome accession   NZ_CP009859
Coordinates   3935328..3935960 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain ECONIH1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3930328..3940960
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ECONIH1_RS19625 (ECONIH1_19625) yheS 3930497..3932410 (+) 1914 WP_000634789.1 ABC transporter ATP-binding protein -
  ECONIH1_RS19630 (ECONIH1_19630) yheT 3932410..3933432 (+) 1023 WP_022646191.1 hydrolase -
  ECONIH1_RS19635 (ECONIH1_19635) yheU 3933426..3933644 (+) 219 WP_000907085.1 YheU family protein -
  ECONIH1_RS19640 (ECONIH1_19640) prkB 3933698..3934567 (+) 870 WP_001274680.1 phosphoribulokinase -
  ECONIH1_RS19645 (ECONIH1_19645) yhfA 3934622..3935026 (-) 405 WP_001148908.1 OsmC family protein -
  ECONIH1_RS19655 (ECONIH1_19655) crp 3935328..3935960 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  ECONIH1_RS19660 (ECONIH1_19660) yhfK 3936011..3938101 (+) 2091 WP_022646192.1 YccS/YhfK family putative transporter -
  ECONIH1_RS19665 (ECONIH1_19665) argD 3938164..3939387 (-) 1224 WP_016233602.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  ECONIH1_RS19670 (ECONIH1_19670) pabA 3939473..3940036 (-) 564 WP_022646193.1 aminodeoxychorismate synthase component 2 -
  ECONIH1_RS19675 (ECONIH1_19675) fic 3940068..3940670 (-) 603 WP_022646194.1 putative adenosine monophosphate-protein transferase Fic -
  ECONIH1_RS19680 (ECONIH1_19680) yhfG 3940660..3940827 (-) 168 WP_022646195.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=114196 ECONIH1_RS19655 WP_000242755.1 3935328..3935960(+) (crp) [Escherichia coli strain ECONIH1]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=114196 ECONIH1_RS19655 WP_000242755.1 3935328..3935960(+) (crp) [Escherichia coli strain ECONIH1]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment