Detailed information NTG1141928

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQK98_RS09825
• Genome accession: NZ_LS483449
• Coordinates: 1846435..1847445 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 4041STDY6836170
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1841435..1852445

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQK98_RS09800	-	1841499..1842713 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
DQK98_RS09805	-	1842869..1843163 (-)	295	Protein_1827	hypothetical protein	-
DQK98_RS09810	-	1843325..1843777 (+)	453	WP_000079148.1	universal stress protein	-
DQK98_RS09815	-	1843812..1845200 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
DQK98_RS09820	-	1845266..1846228 (+)	963	WP_001844919.1	asparaginase	-
DQK98_RS11465	-	1846225..1846371 (-)	147	WP_050097240.1	hypothetical protein	-
DQK98_RS09825	ccpA	1846435..1847445 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
DQK98_RS09830	-	1847870..1848469 (-)	600	WP_000866724.1	response regulator transcription factor	-
DQK98_RS09835	-	1848471..1849568 (-)	1098	WP_000893548.1	sensor histidine kinase	-
DQK98_RS09840	-	1849568..1850305 (-)	738	WP_000832836.1	ABC transporter permease	-
DQK98_RS09845	-	1850307..1851191 (-)	885	WP_000219356.1	ABC transporter ATP-binding protein	-
DQK98_RS09850	-	1851178..1851372 (-)	195	WP_000715301.1	hypothetical protein	-
DQK98_RS09855	-	1851369..1851575 (-)	207	WP_000503440.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=1141928 DQK98_RS09825 WP_000990607.1 1846435..1847445(-) (ccpA) [Streptococcus pneumoniae strain 4041STDY6836170]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=1141928 DQK98_RS09825 WP_000990607.1 1846435..1847445(-) (ccpA) [Streptococcus pneumoniae strain 4041STDY6836170]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568