Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   DQK99_RS10595 Genome accession   NZ_LS483448
Coordinates   1923256..1923558 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836167     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1918256..1928558
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQK99_RS10565 rnpA 1918938..1919309 (-) 372 WP_000739246.1 ribonuclease P protein component -
  DQK99_RS12585 - 1919326..1919457 (-) 132 WP_000768904.1 hypothetical protein -
  DQK99_RS10570 - 1919458..1920648 (-) 1191 WP_000167765.1 acetate kinase -
  DQK99_RS10575 comYH 1920699..1921652 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  DQK99_RS10580 - 1921713..1922305 (-) 593 Protein_1971 class I SAM-dependent methyltransferase -
  DQK99_RS10585 comGG/cglG 1922408..1922854 (-) 447 WP_001809944.1 competence type IV pilus minor pilin ComGG Machinery gene
  DQK99_RS10590 comGF/cglF 1922832..1923293 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQK99_RS10595 comGE/cglE 1923256..1923558 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQK99_RS10600 comGD/cglD 1923521..1923955 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQK99_RS10605 comGC/cglC 1923918..1924241 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  DQK99_RS10610 comGB/cglB 1924243..1925259 (-) 1017 WP_078130737.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQK99_RS10615 comGA/cglA/cilD 1925207..1926148 (-) 942 WP_000249536.1 competence type IV pilus ATPase ComGA Machinery gene
  DQK99_RS10620 - 1926224..1926589 (-) 366 WP_000286415.1 DUF1033 family protein -
  DQK99_RS10625 - 1926740..1927798 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=1141858 DQK99_RS10595 WP_000413382.1 1923256..1923558(-) (comGE/cglE) [Streptococcus pneumoniae strain 4041STDY6836167]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=1141858 DQK99_RS10595 WP_000413382.1 1923256..1923558(-) (comGE/cglE) [Streptococcus pneumoniae strain 4041STDY6836167]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment