Detailed information NTG1141851

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQK99_RS10280
• Genome accession: NZ_LS483448
• Coordinates: 1871980..1872990 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 4041STDY6836167
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1866980..1877990

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQK99_RS10255	-	1867000..1868214 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
DQK99_RS10260	-	1868370..1868664 (-)	295	Protein_1920	hypothetical protein	-
DQK99_RS10265	-	1868826..1869278 (+)	453	WP_000079148.1	universal stress protein	-
DQK99_RS10270	-	1869313..1870701 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
DQK99_RS10275	-	1870767..1871729 (+)	963	WP_001124786.1	asparaginase	-
DQK99_RS11950	-	1871758..1871916 (-)	159	WP_172448389.1	hypothetical protein	-
DQK99_RS10280	ccpA	1871980..1872990 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
DQK99_RS10285	-	1873415..1874014 (-)	600	WP_000866703.1	response regulator transcription factor	-
DQK99_RS10290	-	1874015..1875112 (-)	1098	WP_000893503.1	sensor histidine kinase	-
DQK99_RS10295	-	1875112..1875849 (-)	738	WP_000832916.1	ABC transporter permease	-
DQK99_RS10300	-	1875851..1876735 (-)	885	WP_000219359.1	ABC transporter ATP-binding protein	-
DQK99_RS10305	-	1876722..1876916 (-)	195	WP_000715302.1	hypothetical protein	-
DQK99_RS10310	-	1876913..1877119 (-)	207	Protein_1931	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=1141851 DQK99_RS10280 WP_000990607.1 1871980..1872990(-) (ccpA) [Streptococcus pneumoniae strain 4041STDY6836167]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=1141851 DQK99_RS10280 WP_000990607.1 1871980..1872990(-) (ccpA) [Streptococcus pneumoniae strain 4041STDY6836167]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568