Detailed information NTG1141792

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQN48_RS05955
• Genome accession: NZ_LS483446
• Coordinates: 1250286..1251059 (+)
• Length: 257 a.a.
• NCBI ID: WP_013023452.1
• Uniprot ID: D3UIQ8
• Organism: Helicobacter mustelae strain NCTC12198
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1245286..1256059

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN48_RS05935 (NCTC12198_01150)	-	1246379..1246777 (+)	399	WP_013023448.1	hypothetical protein	-
DQN48_RS05940 (NCTC12198_01151)	-	1246785..1249001 (+)	2217	WP_013023449.1	endonuclease MutS2	-
DQN48_RS05945 (NCTC12198_01152)	minD	1249265..1250059 (+)	795	WP_013023450.1	septum site-determining protein MinD	-
DQN48_RS05950 (NCTC12198_01153)	minE	1250056..1250286 (+)	231	WP_013023451.1	cell division topological specificity factor MinE	-
DQN48_RS05955 (NCTC12198_01154)	dprA	1250286..1251059 (+)	774	WP_013023452.1	DNA-processing protein DprA	Machinery gene
DQN48_RS05960 (NCTC12198_01155)	dprB	1251056..1251454 (+)	399	WP_041913181.1	Holliday junction resolvase RuvX	Machinery gene
DQN48_RS05965 (NCTC12198_01156)	-	1251561..1252565 (-)	1005	WP_013023454.1	glycosyltransferase family 4 protein	-
DQN48_RS05970 (NCTC12198_01157)	-	1252562..1253503 (-)	942	WP_013023455.1	type IV pilus twitching motility protein PilT	-
DQN48_RS05975 (NCTC12198_01158)	-	1253487..1253861 (-)	375	WP_013023456.1	hypothetical protein	-
DQN48_RS05980 (NCTC12198_01159)	-	1253858..1254268 (-)	411	WP_013023457.1	periplasmic protein	-
DQN48_RS05985 (NCTC12198_01160)	-	1254268..1254519 (-)	252	WP_013023458.1	hypothetical protein	-
DQN48_RS05990 (NCTC12198_01161)	-	1254545..1255114 (-)	570	WP_013023459.1	hypothetical protein	-
DQN48_RS05995 (NCTC12198_01162)	-	1255111..1255659 (-)	549	WP_013023460.1	hypothetical protein	-
DQN48_RS06000 (NCTC12198_01164)	-	1255818..1256024 (-)	207	WP_013023461.1	DUF4006 family protein	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28645.25 Da
• Isoelectric Point: 8.4271

>NTDB_id=1141792 DQN48_RS05955 WP_013023452.1 1250286..1251059(+) (dprA) [Helicobacter mustelae strain NCTC12198]
MQSHFDYHPLPQIPESLSALKLQQLFYVGRPELLQSSLKIAIVGSRNPNPYARAFVTQLASKLTPHATIISGGALGIDII
AHKAALPHTIMISPSSLDLIYPASNQHIIKEIAARALILSEYEKNTPPRPYSFLQRNRIVIGLSDIVIIPQADLGSGSMQ
SAKMALKLKKPLYVLPHRINESLGTKSLLSQNQARPIYDIEEFLKECEITPNARDEILEFCAQAPDYEVALEKFGNRLLE
YELDGKIRRENGKVIAL

Nucleotide

• Length: 774 bp

>NTDB_id=1141792 DQN48_RS05955 WP_013023452.1 1250286..1251059(+) (dprA) [Helicobacter mustelae strain NCTC12198]
ATGCAGAGCCATTTTGATTATCACCCCCTCCCACAAATCCCAGAAAGCCTATCTGCACTCAAGCTGCAGCAGCTTTTTTA
TGTGGGCAGGCCAGAGCTCCTGCAATCCTCTCTAAAAATTGCCATTGTTGGCTCGAGGAATCCCAATCCCTATGCCAGAG
CCTTTGTCACACAGCTTGCAAGCAAACTCACTCCCCATGCCACCATTATTAGCGGTGGGGCGCTTGGGATTGACATCATC
GCACACAAAGCAGCACTCCCCCACACCATCATGATTTCACCAAGCAGCCTAGATCTCATCTATCCTGCTAGCAATCAGCA
CATCATCAAAGAAATTGCCGCGCGCGCTCTGATTTTGAGCGAATATGAAAAAAACACACCTCCTAGGCCCTATAGCTTTT
TGCAACGCAATCGCATTGTGATTGGTCTAAGTGATATTGTCATCATCCCTCAAGCAGATCTAGGCAGTGGAAGCATGCAG
AGTGCAAAAATGGCGCTAAAGCTAAAAAAACCCCTCTATGTCCTTCCCCATCGCATCAATGAAAGCCTTGGCACCAAATC
CCTCCTTTCCCAAAATCAGGCAAGGCCAATCTATGATATTGAGGAATTTCTCAAAGAATGTGAAATTACACCAAATGCCA
GAGATGAGATTTTGGAATTTTGCGCACAAGCTCCAGATTATGAAGTGGCACTGGAAAAATTTGGCAATAGGCTTTTGGAA
TATGAGCTAGATGGCAAGATTAGGCGCGAAAATGGCAAGGTGATTGCGCTGTGA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (24-195)

3D structure

• AlphaFold DB: D3UIQ8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Helicobacter pylori 26695	53.409	100	0.549
dprA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	50.222	87.549	0.44