Detailed information NTG1141667

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQN35_RS07145
• Genome accession: NZ_LS483442
• Coordinates: 1389257..1390258 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC8370
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1384257..1395258

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN35_RS07130 (NCTC8370_01415)	thrS	1384427..1386370 (-)	1944	WP_010921984.1	threonine--tRNA ligase	-
DQN35_RS07135 (NCTC8370_01417)	-	1386792..1388126 (-)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
DQN35_RS07140 (NCTC8370_01418)	-	1388128..1389126 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DQN35_RS07145 (NCTC8370_01419)	ccpA	1389257..1390258 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQN35_RS07150 (NCTC8370_01420)	-	1390432..1391517 (+)	1086	WP_002985682.1	aminopeptidase P family protein	-
DQN35_RS07155 (NCTC8370_01421)	-	1391566..1392231 (+)	666	WP_010921982.1	NAD(P)H-dependent oxidoreductase	-
DQN35_RS07160 (NCTC8370_01422)	-	1392242..1392619 (+)	378	WP_002985686.1	VOC family protein	-
DQN35_RS07165 (NCTC8370_01423)	-	1392764..1393690 (+)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
DQN35_RS07170 (NCTC8370_01424)	-	1393901..1394584 (+)	684	WP_002990714.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1141667 DQN35_RS07145 WP_002985680.1 1389257..1390258(-) (ccpA) [Streptococcus pyogenes strain NCTC8370]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1141667 DQN35_RS07145 WP_002985680.1 1389257..1390258(-) (ccpA) [Streptococcus pyogenes strain NCTC8370]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGCCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559