Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DQN45_RS00180 Genome accession   NZ_LS483438
Coordinates   40203..40877 (-) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae strain NCTC12975     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 35203..45877
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN45_RS00160 (NCTC12975_00032) hinT 36905..37255 (+) 351 WP_005627389.1 purine nucleoside phosphoramidase -
  DQN45_RS00165 (NCTC12975_00033) - 37255..37605 (+) 351 WP_005647993.1 DUF1425 domain-containing protein -
  DQN45_RS00170 (NCTC12975_00034) nagZ 37609..38664 (+) 1056 WP_042593724.1 beta-N-acetylhexosaminidase -
  DQN45_RS00175 (NCTC12975_00035) rlmC 38657..39838 (+) 1182 WP_042593723.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  DQN45_RS00180 (NCTC12975_00036) crp 40203..40877 (-) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  DQN45_RS00185 (NCTC12975_00037) - 40862..41113 (-) 252 WP_005647999.1 YheU family protein -
  DQN45_RS00190 (NCTC12975_00038) slmA 41135..41791 (-) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  DQN45_RS00195 (NCTC12975_00039) dut 41795..42250 (-) 456 WP_005631431.1 dUTP diphosphatase -
  DQN45_RS00200 (NCTC12975_00040) coaBC 42298..43500 (-) 1203 WP_011272308.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  DQN45_RS00205 (NCTC12975_00041) radC 43663..44328 (+) 666 WP_013526173.1 DNA repair protein RadC -
  DQN45_RS00210 (NCTC12975_00042) rpmB 44542..44778 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  DQN45_RS00215 (NCTC12975_00043) rpmG 44790..44960 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=1141538 DQN45_RS00180 WP_005647998.1 40203..40877(-) (crp) [Haemophilus influenzae strain NCTC12975]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1141538 DQN45_RS00180 WP_005647998.1 40203..40877(-) (crp) [Haemophilus influenzae strain NCTC12975]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGA
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment