Detailed information NTG1141156

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQN36_RS06985
• Genome accession: NZ_LS483425
• Coordinates: 1401007..1402008 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC13737
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1396007..1407008

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN36_RS06970 (NCTC13737_01380)	thrS	1396177..1398120 (-)	1944	WP_111704297.1	threonine--tRNA ligase	-
DQN36_RS06975 (NCTC13737_01382)	-	1398542..1399876 (-)	1335	WP_111704298.1	glycosyltransferase family 4 protein	-
DQN36_RS06980 (NCTC13737_01383)	-	1399878..1400876 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DQN36_RS06985 (NCTC13737_01384)	ccpA	1401007..1402008 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQN36_RS06990 (NCTC13737_01385)	-	1402182..1403267 (+)	1086	WP_002985682.1	aminopeptidase P family protein	-
DQN36_RS06995 (NCTC13737_01386)	-	1403316..1403981 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DQN36_RS07000 (NCTC13737_01387)	-	1403992..1404369 (+)	378	WP_002985686.1	VOC family protein	-
DQN36_RS07005 (NCTC13737_01388)	-	1404514..1405440 (+)	927	WP_032464862.1	glycosyltransferase family 2 protein	-
DQN36_RS07010 (NCTC13737_01389)	-	1405651..1406334 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1141156 DQN36_RS06985 WP_002985680.1 1401007..1402008(-) (ccpA) [Streptococcus pyogenes strain NCTC13737]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1141156 DQN36_RS06985 WP_002985680.1 1401007..1402008(-) (ccpA) [Streptococcus pyogenes strain NCTC13737]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAACATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAATGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559