Detailed information NTG1141124

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: DQN36_RS00685
• Genome accession: NZ_LS483425
• Coordinates: 104557..104991 (+)
• Length: 144 a.a.
• NCBI ID: WP_063812151.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC13737
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 99557..109991

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN36_RS00655 (NCTC13737_00132)	-	101226..101591 (+)	366	WP_002986560.1	DUF1033 family protein	-
DQN36_RS00660 (NCTC13737_00133)	comYA	101684..102622 (+)	939	WP_063812149.1	competence type IV pilus ATPase ComGA	Machinery gene
DQN36_RS00665 (NCTC13737_00134)	comYB	102558..103592 (+)	1035	WP_225793059.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQN36_RS00670 (NCTC13737_00135)	comYC	103594..103920 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
DQN36_RS00675 (NCTC13737_00136)	comGD	103895..104323 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
DQN36_RS00680 (NCTC13737_00137)	comGE	104280..104564 (+)	285	WP_011284422.1	competence type IV pilus minor pilin ComGE	-
DQN36_RS00685 (NCTC13737_00138)	comYF	104557..104991 (+)	435	WP_063812151.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQN36_RS00690 (NCTC13737_00139)	comGG	104975..105301 (+)	327	WP_010921801.1	competence type IV pilus minor pilin ComGG	-
DQN36_RS00695 (NCTC13737_00140)	comYH	105399..106352 (+)	954	WP_111704429.1	class I SAM-dependent methyltransferase	Machinery gene
DQN36_RS00700 (NCTC13737_00141)	-	106411..107607 (+)	1197	WP_002987791.1	acetate kinase	-
DQN36_RS00705	-	107794..108102 (+)	309	Protein_91	hypothetical protein	-
DQN36_RS00710 (NCTC13737_00142)	proC	108185..108955 (-)	771	WP_111703953.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16671.30 Da
• Isoelectric Point: 10.1914

>NTDB_id=1141124 DQN36_RS00685 WP_063812151.1 104557..104991(+) (comYF) [Streptococcus pyogenes strain NCTC13737]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIYIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1141124 DQN36_RS00685 WP_063812151.1 104557..104991(+) (comYF) [Streptococcus pyogenes strain NCTC13737]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTTACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	44.776	93.056	0.417
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396