Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   DQM62_RS02140 Genome accession   NZ_LS483418
Coordinates   415240..416532 (+) Length   430 a.a.
NCBI ID   WP_014917210.1    Uniprot ID   -
Organism   Streptococcus suis strain NCTC10234     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 410240..421532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM62_RS02115 (NCTC10234_00412) - 411045..411686 (+) 642 WP_002937025.1 response regulator transcription factor -
  DQM62_RS02120 (NCTC10234_00413) - 411736..413136 (+) 1401 WP_011921996.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQM62_RS02125 (NCTC10234_00414) - 413138..413509 (+) 372 WP_011921997.1 S1 RNA-binding domain-containing protein -
  DQM62_RS02130 (NCTC10234_00415) cysK 413535..414461 (-) 927 WP_012774985.1 cysteine synthase A -
  DQM62_RS02135 (NCTC10234_00416) - 414551..415183 (-) 633 WP_014636235.1 YigZ family protein -
  DQM62_RS02140 (NCTC10234_00417) comFA/cflA 415240..416532 (+) 1293 WP_014917210.1 DEAD/DEAH box helicase Machinery gene
  DQM62_RS02145 (NCTC10234_00418) comFC/cflB 416525..417190 (+) 666 WP_004194119.1 ComF family protein Machinery gene
  DQM62_RS02150 (NCTC10234_00419) hpf 417267..417809 (+) 543 WP_004194117.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48974.65 Da        Isoelectric Point: 9.2915

>NTDB_id=1140944 DQM62_RS02140 WP_014917210.1 415240..416532(+) (comFA/cflA) [Streptococcus suis strain NCTC10234]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
PITKCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAADNAVKEAGVQVFLTATSTDEL
DKKVRTGKLSRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSCFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKRKITVLISTTILERGVTFPCVDVFVVQANHYLYTVSSLVQIAGRVGRSMERPTG
LLQFYHEGSTGAIEKAVAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=1140944 DQM62_RS02140 WP_014917210.1 415240..416532(+) (comFA/cflA) [Streptococcus suis strain NCTC10234]
ATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTCGAGCCTGCTTGCTTCTAGGCAGAGTACGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTT
CCAATCACTAAGTGTTTAAAGTGGAAAGGTCAATTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGCGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATCTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCAGTTCCAATTAGTTTACTACATGGAGAGTCTGAACCCTATTTCCGAACCCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCGAGCAGCAGACAATGCGGTCAAGGAAGCTGGTGTTCAAGTTTTTCTGACAGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAACAGGTAAATTAAGTCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAACCCACTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTTCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGTGCTTTCCCTTACTCATTTTTGTCCCAGAAATCTCCAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAAGAG
AAAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTGACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CCAATCATTACCTCTACACAGTGTCAAGTCTTGTTCAGATTGCAGGCCGAGTCGGAAGGAGTATGGAACGTCCGACTGGT
TTACTCCAGTTTTATCATGAGGGAAGTACAGGAGCCATTGAAAAGGCAGTCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(91-235)

Helicase conserved C-terminal domain (Helicase_C)

(294-393)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae Rx1

66.125

100

0.663
  comFA/cflA Streptococcus pneumoniae D39

66.125

100

0.663
  comFA/cflA Streptococcus pneumoniae R6

66.125

100

0.663
  comFA/cflA Streptococcus pneumoniae TIGR4

66.125

100

0.663
  comFA/cflA Streptococcus mitis SK321

65.429

100

0.656
  comFA Lactococcus lactis subsp. cremoris KW2

53.904

92.326

0.498
  comFA Latilactobacillus sakei subsp. sakei 23K

38.051

100

0.381
  comFA Bacillus subtilis subsp. subtilis str. 168

37.349

96.512

0.36

Multiple sequence alignment