Detailed information NTG0114091

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: T303_RS04285
• Genome accession: NZ_CP006819
• Coordinates: 783269..784270 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus ASCC 1275
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 778269..789270

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
T303_RS04265 (T303_04300)	smpB	779376..779840 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
T303_RS04270 (T303_04305)	-	779994..781400 (+)	1407	WP_011680934.1	Cof-type HAD-IIB family hydrolase	-
T303_RS04275 (T303_04310)	-	781402..781767 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
T303_RS04280 (T303_04315)	-	781870..782955 (-)	1086	WP_011680935.1	Xaa-Pro peptidase family protein	-
T303_RS04285 (T303_04320)	ccpA	783269..784270 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
T303_RS10145 (T303_04325)	-	784329..784526 (+)	198	WP_014608125.1	hypothetical protein	-
T303_RS11475	-	784632..784856 (+)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
T303_RS04290 (T303_04330)	-	784857..785396 (+)	540	WP_011680936.1	hypothetical protein	-
T303_RS04295 (T303_04335)	-	785409..786524 (+)	1116	WP_011680937.1	glycerate kinase	-
T303_RS04300 (T303_04340)	-	786571..787026 (-)	456	WP_011680938.1	YueI family protein	-
T303_RS04305 (T303_04345)	eno	787235..788539 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-
T303_RS04310 (T303_04350)	-	788691..788876 (-)	186	WP_011680940.1	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=114091 T303_RS04285 WP_004197422.1 783269..784270(+) (ccpA) [Streptococcus thermophilus ASCC 1275]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=114091 T303_RS04285 WP_004197422.1 783269..784270(+) (ccpA) [Streptococcus thermophilus ASCC 1275]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547