Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DQN24_RS00195 Genome accession   NZ_LS483411
Coordinates   41750..42424 (-) Length   224 a.a.
NCBI ID   WP_032824524.1    Uniprot ID   A0A0K9L2I4
Organism   Haemophilus influenzae strain NCTC11426     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 36750..47424
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN24_RS00175 (NCTC11426_00033) hinT 38458..38808 (+) 351 WP_111695208.1 purine nucleoside phosphoramidase -
  DQN24_RS00180 (NCTC11426_00034) - 38808..39158 (+) 351 WP_111695209.1 YcfL family protein -
  DQN24_RS00185 (NCTC11426_00035) nagZ 39162..40217 (+) 1056 WP_111695210.1 beta-N-acetylhexosaminidase -
  DQN24_RS00190 (NCTC11426_00036) rlmC 40210..41397 (+) 1188 WP_111695211.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  DQN24_RS00195 (NCTC11426_00037) crp 41750..42424 (-) 675 WP_032824524.1 cAMP-activated global transcriptional regulator CRP Regulator
  DQN24_RS00200 (NCTC11426_00038) - 42409..42660 (-) 252 WP_032824522.1 YheU family protein -
  DQN24_RS00205 (NCTC11426_00039) slmA 42683..43339 (-) 657 WP_111695212.1 nucleoid occlusion factor SlmA -
  DQN24_RS00210 (NCTC11426_00040) dut 43343..43798 (-) 456 WP_044330861.1 dUTP diphosphatase -
  DQN24_RS00215 (NCTC11426_00041) coaBC 44367..45581 (-) 1215 WP_111695213.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  DQN24_RS00220 (NCTC11426_00042) radC 45744..46409 (+) 666 WP_050846688.1 RadC family protein -
  DQN24_RS00225 (NCTC11426_00043) rpmB 46622..46858 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  DQN24_RS00230 (NCTC11426_00044) rpmG 46870..47040 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25076.74 Da        Isoelectric Point: 6.6042

>NTDB_id=1140640 DQN24_RS00195 WP_032824524.1 41750..42424(-) (crp) [Haemophilus influenzae strain NCTC11426]
MSNELTEVDDVVTSPQEETTPNDPILDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVSNLAFLDVAGRIAQ
TLMNLAKQPDAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1140640 DQN24_RS00195 WP_032824524.1 41750..42424(-) (crp) [Haemophilus influenzae strain NCTC11426]
ATGTCAAATGAATTAACTGAAGTTGATGATGTTGTAACATCTCCGCAGGAAGAAACAACACCGAATGATCCCATTTTAGA
TTGGTTTCTTACCCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCACGCAGGGGAAGATGCGACTACGT
TGTATTATGTAATTAAAGGCTCTGTAATGGTGTCTTCAAAAGATGATGAAGGCAAAGAGATGATTCTCACTTACTTAGGT
GCAGGACAATTTTTTGGAGAAGCGGGATTATTTGATGAGGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAGATTTCTTATAAAAAATATCGTCAATTAATTCAAGCAAACCCAGAAATCTTAATGTTTTTAACCGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTAAGTAACCTTGCATTCTTAGATGTAGCAGGGCGTATCGCTCAA
ACACTGATGAATTTAGCTAAACAACCCGATGCAATGACCCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGGGAAACTGTGGGACGAATTATCAAGATGTTAGAGGATCAGAACCTTATTCATGCCC
ATGGAAAAACCATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K9L2I4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

95.982

100

0.96
  crp Vibrio cholerae strain A1552

73.364

95.536

0.701
  crp Acinetobacter baumannii D1279779

47.668

86.161

0.411

Multiple sequence alignment