Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   DQN67_RS13535 Genome accession   NZ_LS483410
Coordinates   2985216..2985875 (-) Length   219 a.a.
NCBI ID   WP_011947563.1    Uniprot ID   -
Organism   Legionella pneumophila strain NCTC11404     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2980216..2990875
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN67_RS13520 (NCTC11404_02679) - 2981115..2981774 (+) 660 WP_013101910.1 hypothetical protein -
  DQN67_RS13525 (NCTC11404_02680) lcl 2981942..2983324 (+) 1383 WP_014844754.1 collagen-like adhesin Lcl -
  DQN67_RS13530 (NCTC11404_02681) uvrC 2983348..2985204 (-) 1857 WP_014844755.1 excinuclease ABC subunit UvrC -
  DQN67_RS13535 (NCTC11404_02682) letA 2985216..2985875 (-) 660 WP_011947563.1 two-component system response regulator LetA Regulator
  DQN67_RS13540 (NCTC11404_02683) phhA 2986000..2986818 (-) 819 WP_014844756.1 phenylalanine 4-monooxygenase -
  DQN67_RS13545 (NCTC11404_02684) - 2987262..2988359 (+) 1098 WP_014844757.1 competence/damage-inducible protein A -
  DQN67_RS13550 (NCTC11404_02685) cgtA 2988318..2989343 (-) 1026 WP_014844758.1 Obg family GTPase CgtA -
  DQN67_RS13555 (NCTC11404_02686) rpmA 2989558..2989836 (-) 279 WP_010948350.1 50S ribosomal protein L27 -
  DQN67_RS13560 (NCTC11404_02687) rplU 2989849..2990160 (-) 312 WP_010948351.1 50S ribosomal protein L21 -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24566.53 Da        Isoelectric Point: 5.1572

>NTDB_id=1140633 DQN67_RS13535 WP_011947563.1 2985216..2985875(-) (letA) [Legionella pneumophila strain NCTC11404]
MIKVLIVDDHALVRMGIRRLLEDMSDVDVVADAESGEQALAYVKTHSPDVVLLDMKMPGIDGWEVTRRLKKTNPNIKVIA
VTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLQEPQDSPFDLLSEREMQVMLMI
TSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNDLSQDD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1140633 DQN67_RS13535 WP_011947563.1 2985216..2985875(-) (letA) [Legionella pneumophila strain NCTC11404]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTAGAATGGGCATTCGACGATTGCTTGAAGATATGTCGGATGT
TGATGTGGTTGCAGATGCTGAAAGTGGGGAGCAGGCTTTAGCTTATGTGAAAACCCACTCCCCTGATGTCGTATTATTAG
ACATGAAAATGCCTGGGATAGATGGGTGGGAAGTGACGCGTCGCTTAAAAAAAACAAACCCAAATATTAAAGTCATAGCC
GTTACAGCTATTTGCTCAGATCCTCTCCCTACTCGAGTATTGCAATTAGGTGCTATGGGATACCTTACTAAAGAATCAGG
GGCTGAAGAAATGGCTGCTGCAATTCGTAAAGTGGCTAAAGGTGAGAAATATCTTAGTGCCGAGATTGCACAAAAAATGG
CAATTAATAGTCTTCAGGAGCCTCAAGATTCCCCCTTTGATTTATTGTCTGAAAGAGAAATGCAAGTCATGTTGATGATT
ACGAGCGGCATGAATGTACAAGACATTGCTGATAGATTATTTTTAAGTAGTAAAACCATCAATGGTTATCGATATAGGAT
GTTTGAAAAATTGGGGATTAAAAATGATGTGGAGCTTACTTATTTGGCTATGAAGCACCGCATTATTGAACACCCCAATG
ATTTGTCACAAGATGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

100

100

1
  letA Legionella pneumophila strain ERS1305867

100

100

1

Multiple sequence alignment