Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   DQN21_RS03115 Genome accession   NZ_LS483409
Coordinates   563289..564590 (+) Length   433 a.a.
NCBI ID   WP_074658789.1    Uniprot ID   A0A1I7JQ11
Organism   Streptococcus gallolyticus strain NCTC13773     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 558289..569590
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN21_RS03090 (NCTC13773_00622) - 558940..559584 (+) 645 WP_009853571.1 response regulator transcription factor -
  DQN21_RS03095 (NCTC13773_00623) - 559703..561103 (+) 1401 WP_077496363.1 Cof-type HAD-IIB family hydrolase -
  DQN21_RS03100 (NCTC13773_00624) - 561103..561459 (+) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -
  DQN21_RS03105 (NCTC13773_00625) cysK 561573..562502 (-) 930 WP_012961540.1 cysteine synthase A -
  DQN21_RS03110 (NCTC13773_00626) - 562606..563232 (-) 627 WP_074658787.1 YigZ family protein -
  DQN21_RS03115 (NCTC13773_00627) comFA/cflA 563289..564590 (+) 1302 WP_074658789.1 DEAD/DEAH box helicase Machinery gene
  DQN21_RS03120 (NCTC13773_00628) comFC/cflB 564587..565249 (+) 663 WP_077496365.1 ComF family protein Machinery gene
  DQN21_RS03125 (NCTC13773_00629) hpf 565325..565873 (+) 549 WP_003063557.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49185.34 Da        Isoelectric Point: 9.9214

>NTDB_id=1140553 DQN21_RS03115 WP_074658789.1 563289..564590(+) (comFA/cflA) [Streptococcus gallolyticus strain NCTC13773]
MDKLDNYYGRLFTQAQLSDALKKHAKQLPAMTKLNHHYVCNRCGSQVSLQNKLQTNVFYCRNCLVFGRNTSNGHLYYFPQ
KRFSKKDSLIWKGKLTPYQDDVSKGMLEGIDAKKDLLIHAVTGAGKTEMIYQSVSKIIDDGGCVCLASPRIDVCLELYKR
LSRDFSYPITLLHGDSEPYKRAPLIIATTHQLLKFYQAFDLLIIDEVDAFPFVDNAVLYHAVDKAIKPNGTKIFLTATST
DELDKKVKTGTLTKLHLARRFHANPLVVPQKIWLSGVLSNMQKKKIPQKLINLLKKQRQTCYPLLIFFPNIEQGEAFTQI
LQTYFPEEQIAFVSSKTENRLEIVEKFRKQELSILVTTTILERGVTFPCVDVFVVLANHRLYTKSALVQISGRVGRAAER
PTGELLFLHDGSTKEMRKAIAEIKAMNKKGGFA

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=1140553 DQN21_RS03115 WP_074658789.1 563289..564590(+) (comFA/cflA) [Streptococcus gallolyticus strain NCTC13773]
ATGGATAAACTGGATAATTATTATGGAAGACTATTTACACAAGCTCAACTTTCGGATGCCTTAAAAAAGCATGCTAAACA
GTTGCCAGCAATGACAAAATTAAATCATCATTATGTTTGCAATCGTTGTGGTAGTCAAGTGTCTTTACAAAATAAACTTC
AAACAAACGTTTTTTATTGTCGAAATTGCCTTGTTTTTGGAAGAAATACGAGTAATGGACATCTCTATTATTTTCCACAA
AAACGTTTTTCTAAAAAAGATTCTCTTATTTGGAAAGGAAAATTGACTCCTTACCAAGATGACGTTTCAAAAGGGATGTT
AGAAGGCATTGATGCTAAGAAAGACCTACTTATTCATGCTGTTACAGGTGCTGGAAAAACAGAAATGATTTACCAATCTG
TATCCAAAATAATTGATGACGGTGGTTGTGTTTGCCTAGCAAGTCCGCGAATTGATGTTTGTCTGGAGCTTTATAAACGC
TTGTCACGTGATTTTTCGTATCCGATTACATTGCTTCATGGAGATTCTGAACCCTACAAACGTGCCCCTTTAATCATTGC
CACAACACATCAACTTTTAAAATTTTACCAAGCTTTTGATTTGTTAATTATTGATGAAGTTGATGCCTTTCCATTTGTGG
ATAATGCCGTGCTTTACCATGCTGTTGATAAAGCTATCAAACCTAATGGAACCAAGATTTTTTTAACAGCGACATCAACA
GATGAATTAGATAAAAAAGTAAAAACAGGAACTCTGACCAAATTGCACCTTGCTCGACGCTTTCATGCCAATCCATTAGT
TGTGCCACAAAAAATCTGGTTGTCTGGCGTTTTATCCAATATGCAAAAGAAGAAAATTCCCCAGAAATTAATAAATCTTC
TAAAAAAACAACGTCAAACCTGCTATCCTTTGCTAATTTTCTTCCCAAATATCGAACAAGGAGAAGCCTTTACTCAAATT
TTACAAACTTACTTTCCAGAAGAACAAATCGCTTTTGTGTCTAGTAAAACAGAAAATCGCTTAGAAATTGTAGAAAAATT
TAGGAAACAAGAACTTTCTATTTTGGTAACAACAACCATTTTAGAACGTGGTGTCACTTTCCCATGCGTAGATGTTTTTG
TAGTGCTTGCCAATCATAGATTATACACCAAAAGCGCGCTAGTTCAGATTTCAGGGCGAGTTGGGAGAGCAGCAGAGCGT
CCAACAGGAGAACTGTTATTCTTGCATGACGGTAGCACTAAAGAAATGAGAAAAGCTATTGCTGAAATTAAAGCGATGAA
TAAAAAAGGAGGATTTGCATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(287-397)

DEAD/DEAH box helicase (DEAD)

(96-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1I7JQ11

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae TIGR4

60.187

98.614

0.594
  comFA/cflA Streptococcus pneumoniae Rx1

60.187

98.614

0.594
  comFA/cflA Streptococcus pneumoniae D39

60.187

98.614

0.594
  comFA/cflA Streptococcus pneumoniae R6

60.187

98.614

0.594
  comFA/cflA Streptococcus mitis NCTC 12261

59.953

98.614

0.591
  comFA/cflA Streptococcus mitis SK321

59.251

98.614

0.584
  comFA Lactococcus lactis subsp. cremoris KW2

50.735

94.226

0.478
  comFA Latilactobacillus sakei subsp. sakei 23K

38.161

100

0.383

Multiple sequence alignment