Detailed information NTG1140283

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQM79_RS02295
• Genome accession: NZ_LS483401
• Coordinates: 419316..420317 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC10085
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 414316..425317

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM79_RS02270 (NCTC10085_00442)	-	414990..415673 (-)	684	WP_002990714.1	DUF969 domain-containing protein	-
DQM79_RS02275 (NCTC10085_00443)	-	415884..416810 (-)	927	WP_002990711.1	glycosyltransferase family 2 protein	-
DQM79_RS02280 (NCTC10085_00444)	-	416955..417332 (-)	378	WP_002985686.1	VOC family protein	-
DQM79_RS02285 (NCTC10085_00445)	-	417343..418008 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DQM79_RS02290 (NCTC10085_00446)	-	418057..419142 (-)	1086	WP_002990707.1	aminopeptidase P family protein	-
DQM79_RS02295 (NCTC10085_00447)	ccpA	419316..420317 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQM79_RS02300 (NCTC10085_00448)	-	420448..421446 (+)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
DQM79_RS02305 (NCTC10085_00449)	-	421448..422782 (+)	1335	WP_002990700.1	glycosyltransferase family 4 protein	-
DQM79_RS02310 (NCTC10085_00451)	thrS	423204..425147 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1140283 DQM79_RS02295 WP_002985680.1 419316..420317(+) (ccpA) [Streptococcus pyogenes strain NCTC10085]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1140283 DQM79_RS02295 WP_002985680.1 419316..420317(+) (ccpA) [Streptococcus pyogenes strain NCTC10085]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559