Detailed information NTG1140223

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQM80_RS02125
• Genome accession: NZ_LS483399
• Coordinates: 393618..394619 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC8227
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 388618..399619

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM80_RS02100 (NCTC8227_00411)	-	389292..389975 (-)	684	WP_011017476.1	DUF969 domain-containing protein	-
DQM80_RS02105 (NCTC8227_00412)	-	390186..391112 (-)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
DQM80_RS02110 (NCTC8227_00413)	-	391257..391634 (-)	378	WP_002985686.1	VOC family protein	-
DQM80_RS02115 (NCTC8227_00414)	-	391645..392310 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DQM80_RS02120 (NCTC8227_00415)	-	392359..393444 (-)	1086	WP_002985682.1	aminopeptidase P family protein	-
DQM80_RS02125 (NCTC8227_00416)	ccpA	393618..394619 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQM80_RS02130 (NCTC8227_00417)	-	394750..395748 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DQM80_RS02135 (NCTC8227_00418)	-	395750..397084 (+)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
DQM80_RS02140 (NCTC8227_00420)	thrS	397506..399449 (+)	1944	WP_111701863.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1140223 DQM80_RS02125 WP_002985680.1 393618..394619(+) (ccpA) [Streptococcus pyogenes strain NCTC8227]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1140223 DQM80_RS02125 WP_002985680.1 393618..394619(+) (ccpA) [Streptococcus pyogenes strain NCTC8227]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559