Detailed information NTG1140157

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQM95_RS03205
• Genome accession: NZ_LS483397
• Coordinates: 556874..557875 (+)
• Length: 333 a.a.
• NCBI ID: WP_012658062.1
• Uniprot ID: A0A2X4GXW1
• Organism: Streptococcus uberis strain NCTC3858
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 551874..562875

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM95_RS03180 (NCTC3858_00644)	-	552189..552503 (+)	315	WP_012658057.1	PTS cellobiose transporter subunit IIA	-
DQM95_RS03185 (NCTC3858_00645)	-	552529..553047 (+)	519	WP_012658058.1	hypothetical protein	-
DQM95_RS03190 (NCTC3858_00646)	celB	553074..554402 (+)	1329	WP_037592366.1	PTS cellobiose transporter subunit IIC	-
DQM95_RS03195 (NCTC3858_00647)	-	554468..555556 (+)	1089	WP_037592365.1	DUF871 domain-containing protein	-
DQM95_RS03200 (NCTC3858_00648)	-	555617..556702 (-)	1086	WP_037592364.1	aminopeptidase P family protein	-
DQM95_RS03205 (NCTC3858_00649)	ccpA	556874..557875 (+)	1002	WP_012658062.1	catabolite control protein A	Regulator
DQM95_RS03210 (NCTC3858_00650)	-	557916..559385 (+)	1470	WP_037592363.1	alpha-amylase	-
DQM95_RS03215 (NCTC3858_00651)	-	559459..560457 (+)	999	WP_037592362.1	glycosyltransferase family 4 protein	-
DQM95_RS03220 (NCTC3858_00652)	-	560459..561793 (+)	1335	WP_012658065.1	glycosyltransferase family 4 protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36662.76 Da
• Isoelectric Point: 5.5101

>NTDB_id=1140157 DQM95_RS03205 WP_012658062.1 556874..557875(+) (ccpA) [Streptococcus uberis strain NCTC3858]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANAYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPIVLAGTVDLEHQLPS
VNIDYQAAVAEVIDILAENHKKIAFVSGPLIDDINGKVRLSGYKEGLKKNKLDYKEGLVFEANYSYKEGYELAQRVINSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVVEYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKRRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1140157 DQM95_RS03205 WP_012658062.1 556874..557875(+) (ccpA) [Streptococcus uberis strain NCTC3858]
ATGAACACAGATGATACCATTACGATTTATGATGTTGCTCGTGAAGCTGGTGTTTCAATGGCAACTGTCAGCCGTGTTGT
AAATGGAAATAAAAACGTTAAGGAAAATACACGCAAAAAAGTTTTAGAAGTTATCGATCGTTTAGATTATCGTCCTAACG
CCGTCGCTCGTGGACTTGCAAGTAAGAAAACAACAACTGTTGGTGTTGTTATTCCAAATATTGCCAATGCCTATTTTTCA
ATTTTAGCCAAAGGTATTGATGATATCGCAGCCATGTACAAATATAACATTGTCTTGGCATCTAGTGACGAGGACGATGA
TAAAGAAGTCAATGTTGTCAATACCCTCTTTGCCAAACAAGTTGATGGGATTATTTTCATGGGTCACCATTTAACAGAAA
AAATTCGTGCAGAATTTTCACGTTCTAGAACCCCTATCGTTTTAGCAGGTACCGTTGACCTTGAACACCAACTTCCAAGC
GTTAATATTGACTATCAAGCAGCAGTCGCTGAGGTTATTGATATTTTAGCAGAGAACCATAAGAAAATCGCATTTGTATC
AGGTCCACTTATTGATGATATCAATGGTAAAGTACGTCTTTCTGGTTATAAAGAAGGCCTTAAAAAGAATAAATTAGATT
ATAAAGAAGGCTTAGTCTTTGAAGCCAATTATTCTTACAAAGAAGGCTATGAATTGGCACAGCGTGTGATTAATTCTGGA
GCAACTGCAGCTTATGTCGGTGAAGATGAATTAGCAGCTGGTTTATTAAATGGTCTCTTTGCGGCAGGAAAAAGTGTACC
TGAAGATTTTGAAATCATTACAAGTAATGATTCACCTGTTGTTGAATACACTCGTCCTAACTTGAGTTCAATTAGTCAAC
CAGTTTATGATTTAGGTGCCGTAAGTATGCGTATGTTAACAAAAATCATGAACAAAGAAGAATTAGAAGAAAAAGAGATT
CTATTAAACCATGGCATCAAACGTCGTGGAACAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A2X4GXW1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	79.279	100	0.793
ccpA	Streptococcus pneumoniae D39	76.877	100	0.769
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	55.287	99.399	0.55