Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   DQM67_RS06195 Genome accession   NZ_LS483383
Coordinates   1225137..1226366 (-) Length   409 a.a.
NCBI ID   WP_005589758.1    Uniprot ID   A0A0F2CWF6
Organism   Streptococcus cristatus ATCC 51100 strain NCTC 12479     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1220137..1231366
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM67_RS06165 (NCTC12479_01192) rplJ 1220352..1220852 (-) 501 WP_001287273.1 50S ribosomal protein L10 -
  DQM67_RS06170 (NCTC12479_01194) - 1221085..1221426 (-) 342 WP_005589765.1 hypothetical protein -
  DQM67_RS06175 (NCTC12479_01195) - 1221555..1222352 (-) 798 WP_005589763.1 formate/nitrite transporter family protein -
  DQM67_RS06180 (NCTC12479_01196) mmuM 1222466..1223410 (-) 945 WP_005589761.1 homocysteine S-methyltransferase -
  DQM67_RS06185 (NCTC12479_01197) - 1223549..1224247 (-) 699 WP_005589760.1 glucosaminidase domain-containing protein -
  DQM67_RS06190 (NCTC12479_01198) yihA 1224540..1225127 (-) 588 WP_005589759.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  DQM67_RS06195 (NCTC12479_01199) clpX 1225137..1226366 (-) 1230 WP_005589758.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  DQM67_RS06205 (NCTC12479_01201) - 1226583..1227095 (-) 513 WP_005592247.1 dihydrofolate reductase -
  DQM67_RS06210 (NCTC12479_01202) - 1227249..1227734 (-) 486 WP_005592214.1 hypothetical protein -
  DQM67_RS06215 (NCTC12479_01203) - 1227869..1228708 (-) 840 WP_111705358.1 thymidylate synthase -
  DQM67_RS06220 (NCTC12479_01204) - 1228793..1229200 (-) 408 WP_005589752.1 hypothetical protein -
  DQM67_RS06225 (NCTC12479_01205) - 1229246..1230205 (-) 960 WP_005592184.1 ROK family glucokinase -
  DQM67_RS06230 (NCTC12479_01206) endA 1230412..1231260 (-) 849 WP_005589748.1 DNA/RNA non-specific endonuclease Machinery gene

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45456.92 Da        Isoelectric Point: 4.4356

>NTDB_id=1139507 DQM67_RS06195 WP_005589758.1 1225137..1226366(-) (clpX) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
MPTNRNNEMMVYCSFCGKNQDEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLNILNHYVIGQDR
AKRALAVAVYNHYKRINFHDSREEDDVELQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATALTEAGYVGEDVENI
LLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDEGASYMQAIVADDIQKFGIIPELIGRLPVFAALEQLTVDDLVRI
LSEPRNALVKQYQTLLSYDDVELEFDEEALQAIARKAIERKTGARGLRSIIEETMMDVMFEVPSQENVKLVRITKEAVDG
TDKPILETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=1139507 DQM67_RS06195 WP_005589758.1 1225137..1226366(-) (clpX) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
ATGCCTACAAATCGTAATAATGAGATGATGGTATATTGTTCTTTCTGTGGAAAGAATCAGGACGAAGTCCAAAAGATTAT
TGCGGGCAACAATGCCTTTATCTGTAATGAATGTGTCGAGTTGGCGCAGGAAATTATTCGAGAAGAATTAGCTGAGGAAG
TTTTAGCTGATCTTTCTGAAGTACCAAAACCGCAAGAATTGCTCAATATTTTGAACCACTATGTGATTGGTCAAGATCGG
GCCAAGCGGGCTTTGGCAGTTGCCGTTTACAATCACTATAAGCGAATTAATTTTCATGACAGTCGCGAAGAGGATGATGT
GGAGCTACAAAAATCCAACATCCTCATGATTGGTCCAACTGGATCTGGGAAAACATTCCTGGCTCAGACCTTGGCGCGCA
GTCTCAATGTTCCTTTTGCTATCGCGGATGCGACAGCCTTGACTGAGGCTGGCTATGTTGGTGAAGATGTAGAGAATATC
CTGCTCAAGCTTTTACAGGCAGCTGATTTCAATATTGAACGGGCAGAACGCGGCATCATTTATGTGGATGAAATCGACAA
GATTGCTAAGAAGAGCGAAAATGTTTCTATCACTCGTGATGTTTCAGGTGAGGGTGTTCAGCAAGCCTTACTGAAGATTA
TTGAAGGAACAGTTGCCAGCGTGCCTCCTCAAGGTGGTCGTAAGCATCCACAGCAAGAAATGATTCAGGTTGATACCAAG
AACATTCTCTTTATCGTTGGTGGTGCTTTTGATGGTATCGAAGAGATTGTCAAGCAACGTCTTGGTGAGAAGATTATCGG
TTTCGGTCAAAACAATAAGGCAATCGACGAGGGTGCGTCTTATATGCAGGCCATTGTCGCTGACGATATTCAAAAATTTG
GGATTATTCCTGAGTTGATTGGTCGTTTGCCAGTTTTTGCAGCTCTAGAGCAGCTGACCGTTGATGATTTAGTTCGCATT
TTGAGTGAACCGAGAAATGCACTAGTGAAGCAATACCAAACCTTGCTTTCTTATGATGATGTTGAGCTTGAATTTGACGA
GGAAGCTTTGCAAGCCATTGCTAGAAAAGCTATCGAACGCAAGACAGGTGCGCGTGGACTGCGTTCAATTATTGAAGAAA
CCATGATGGATGTCATGTTTGAAGTGCCAAGTCAGGAAAATGTCAAACTGGTTCGTATCACGAAGGAAGCAGTGGACGGC
ACAGACAAGCCAATCTTAGAAACTGCCTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F2CWF6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.553

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.354

98.044

0.572

Multiple sequence alignment