Detailed information NTG1139508

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: DQM67_RS06230
• Genome accession: NZ_LS483383
• Coordinates: 1230412..1231260 (-)
• Length: 282 a.a.
• NCBI ID: WP_005589748.1
• Uniprot ID: A0AAV3EEY6
• Organism: Streptococcus cristatus ATCC 51100 strain NCTC 12479
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1225412..1236260

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM67_RS06205 (NCTC12479_01201)	-	1226583..1227095 (-)	513	WP_005592247.1	dihydrofolate reductase	-
DQM67_RS06210 (NCTC12479_01202)	-	1227249..1227734 (-)	486	WP_005592214.1	hypothetical protein	-
DQM67_RS06215 (NCTC12479_01203)	-	1227869..1228708 (-)	840	WP_111705358.1	thymidylate synthase	-
DQM67_RS06220 (NCTC12479_01204)	-	1228793..1229200 (-)	408	WP_005589752.1	hypothetical protein	-
DQM67_RS06225 (NCTC12479_01205)	-	1229246..1230205 (-)	960	WP_005592184.1	ROK family glucokinase	-
DQM67_RS06230 (NCTC12479_01206)	endA	1230412..1231260 (-)	849	WP_005589748.1	DNA/RNA non-specific endonuclease	Machinery gene
DQM67_RS06235 (NCTC12479_01207)	-	1231332..1231520 (-)	189	WP_005592154.1	DNA-directed RNA polymerase subunit beta	-
DQM67_RS06240 (NCTC12479_01208)	murA	1231513..1232793 (-)	1281	WP_005589744.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
DQM67_RS06245 (NCTC12479_01209)	-	1232862..1233092 (-)	231	WP_005589742.1	DUF1146 family protein	-
DQM67_RS06250 (NCTC12479_01210)	-	1233180..1233602 (-)	423	WP_005589741.1	F0F1 ATP synthase subunit epsilon	-
DQM67_RS06255 (NCTC12479_01211)	atpD	1233610..1235016 (-)	1407	WP_005589740.1	F0F1 ATP synthase subunit beta	-
DQM67_RS06260 (NCTC12479_01212)	-	1235054..1235932 (-)	879	WP_005589739.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 30520.00 Da
• Isoelectric Point: 10.1511

>NTDB_id=1139508 DQM67_RS06230 WP_005589748.1 1230412..1231260(-) (endA) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
MPKRKKLQKKSTKSTQTIAGLLVALTLSLGAYFFGNGNQSPAVNTSSAISQNRDTSTPDQALAESVLTDSVRSQLGGKIE
WNGAGAFIINGNQTNLDAKVSSAPYADNKTKMVQGQTVPTVANALLAKSTRQYKSREETGNGSTSWVPAGWHQVKYLSGE
YNHAVDRGHLLAYSLIGGLKGFDASTSNPANIAVQTAWANQANKDNSTGQNYYETQIRRALDQNKRVRYRVTLIYASEND
LVPSGSHLEAKSSDGSLEFNVFVPNVQSGIVLDYRTGRVSLR

Nucleotide

• Length: 849 bp

>NTDB_id=1139508 DQM67_RS06230 WP_005589748.1 1230412..1231260(-) (endA) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
ATGCCAAAAAGAAAGAAATTACAAAAAAAGAGCACTAAATCTACTCAGACTATAGCTGGGCTTCTGGTTGCTCTGACTTT
ATCACTGGGAGCCTACTTTTTTGGAAATGGCAATCAGTCACCAGCGGTAAATACATCGTCAGCCATTAGTCAAAATAGGG
ATACCAGCACACCAGATCAAGCACTGGCTGAGAGTGTTCTCACTGACTCGGTGCGTTCTCAACTTGGTGGAAAAATCGAG
TGGAATGGAGCTGGAGCTTTCATCATCAATGGGAATCAAACGAACTTAGATGCCAAAGTGTCGAGTGCCCCTTATGCGGA
TAATAAAACGAAGATGGTTCAGGGGCAGACTGTTCCAACAGTTGCCAATGCCTTGCTTGCCAAATCGACCCGTCAATATA
AATCAAGGGAAGAAACGGGAAATGGTTCCACTTCTTGGGTTCCTGCTGGTTGGCACCAAGTCAAATATCTATCAGGTGAA
TACAACCATGCAGTGGATCGCGGGCATCTTTTGGCTTACTCTCTTATCGGTGGTTTAAAGGGATTCGACGCCTCTACTAG
CAATCCAGCCAATATCGCAGTCCAAACAGCCTGGGCCAATCAGGCCAATAAAGACAATTCGACGGGCCAGAATTACTATG
AAACTCAGATTCGTCGTGCTTTGGACCAGAATAAGCGAGTCCGCTATCGTGTCACGTTGATCTATGCTTCAGAAAATGAT
CTGGTGCCATCTGGCTCGCATTTAGAAGCTAAGTCCAGCGATGGAAGTTTGGAATTCAATGTCTTCGTTCCCAATGTCCA
GTCAGGAATAGTCCTTGATTATCGCACTGGCAGAGTGAGCCTTAGATAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (85-256)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	69.145	95.39	0.66
endA	Streptococcus pneumoniae D39	69.145	95.39	0.66
endA	Streptococcus pneumoniae R6	69.145	95.39	0.66
endA	Streptococcus pneumoniae TIGR4	69.145	95.39	0.66