Detailed information NTG1139446

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQM89_RS02270
• Genome accession: NZ_LS483382
• Coordinates: 415628..416629 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC13738
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 410628..421629

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM89_RS02245 (NCTC13738_00441)	-	411302..411985 (-)	684	WP_012560521.1	DUF969 domain-containing protein	-
DQM89_RS02250 (NCTC13738_00442)	-	412196..413122 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
DQM89_RS02255 (NCTC13738_00443)	-	413267..413644 (-)	378	WP_002985686.1	VOC family protein	-
DQM89_RS02260 (NCTC13738_00444)	-	413655..414320 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DQM89_RS02265 (NCTC13738_00445)	-	414369..415454 (-)	1086	WP_076634295.1	aminopeptidase P family protein	-
DQM89_RS02270 (NCTC13738_00446)	ccpA	415628..416629 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
DQM89_RS02275 (NCTC13738_00447)	-	416760..417758 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DQM89_RS02280 (NCTC13738_00448)	-	417760..419094 (+)	1335	WP_002985676.1	glycosyltransferase family 4 protein	-
DQM89_RS02285 (NCTC13738_00450)	thrS	419516..421459 (+)	1944	WP_076634296.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1139446 DQM89_RS02270 WP_002985680.1 415628..416629(+) (ccpA) [Streptococcus pyogenes strain NCTC13738]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1139446 DQM89_RS02270 WP_002985680.1 415628..416629(+) (ccpA) [Streptococcus pyogenes strain NCTC13738]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGTAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAATGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559