Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   DQM69_RS07840 Genome accession   NZ_LS483381
Coordinates   1627244..1628605 (-) Length   453 a.a.
NCBI ID   WP_019770277.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NCTC10921     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1622244..1633605
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM69_RS07825 (NCTC10921_01556) trkA 1623333..1624682 (+) 1350 WP_019777040.1 Trk system potassium transporter TrkA -
  DQM69_RS07830 (NCTC10921_01557) - 1624693..1626132 (+) 1440 WP_109982704.1 TrkH family potassium uptake protein -
  DQM69_RS07835 (NCTC10921_01558) vicX 1626442..1627251 (-) 810 WP_109982705.1 MBL fold metallo-hydrolase Regulator
  DQM69_RS07840 (NCTC10921_01559) vicK 1627244..1628605 (-) 1362 WP_019770277.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQM69_RS07845 (NCTC10921_01560) vicR 1628598..1629305 (-) 708 WP_109982820.1 response regulator YycF Regulator
  DQM69_RS07850 (NCTC10921_01561) - 1629531..1630295 (+) 765 WP_002960993.1 amino acid ABC transporter ATP-binding protein -
  DQM69_RS07855 (NCTC10921_01562) - 1630309..1631133 (+) 825 WP_019784970.1 transporter substrate-binding domain-containing protein -
  DQM69_RS07860 (NCTC10921_01563) - 1631149..1631856 (+) 708 WP_002960990.1 amino acid ABC transporter permease -
  DQM69_RS07865 (NCTC10921_01564) - 1631871..1632521 (+) 651 WP_019790209.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 51817.30 Da        Isoelectric Point: 4.3763

>NTDB_id=1139405 DQM69_RS07840 WP_019770277.1 1627244..1628605(-) (vicK) [Streptococcus sobrinus strain NCTC10921]
MNNNPVVENLNTFELALLILLALVALYFIYQAVREYRNAKTVRAISQKVTSLIAGDYTEDLHLKGDSELIELGTNLNDLS
DVLHLTHENLSQERNRLASVLSYMSDGVLATNRVGKITMINDTARKQLNLTREEALEMNIMDLIDSDDYDYRDLITQTPE
VTLYRRNEYDEFITLRVNFALNRRESGFISGLVAVLHDTTEQEKEERERRLFVSTVSHELRTPLTSVKSYLEALNEGALN
EDVAPSFIQVSLDETNRMMRMISDLLQLSRIDNDTSHLEVEMTNFTAFITVILNRFDQIKSQQDSDKDYEIVRNYPLNPI
WVEIDTDKMTQVLDNILNNAIKYSPDGGEITVSMTTTDTQLIISISDQGLGIPKKDLPMIFDRFYRVDKARSRAQGGTGL
GLAIAKEIIKQHHGFIWAKSEYGKGSTFTIVLPYDKEPDDFDDEWEEEESVND

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=1139405 DQM69_RS07840 WP_019770277.1 1627244..1628605(-) (vicK) [Streptococcus sobrinus strain NCTC10921]
ATGAATAATAATCCTGTTGTTGAAAATCTCAATACCTTTGAATTAGCCCTGCTCATTCTTTTGGCCCTAGTTGCCCTTTA
TTTTATTTATCAAGCAGTGCGGGAGTACCGCAATGCTAAGACCGTTCGTGCTATTAGCCAAAAGGTAACCAGCCTGATTG
CTGGTGATTACACGGAGGATCTTCACTTAAAAGGGGATTCTGAATTGATTGAGCTGGGGACCAACTTGAATGACCTGTCA
GATGTTTTGCATTTGACCCATGAAAATCTTTCACAAGAGCGCAATCGCCTAGCTTCCGTCCTGTCCTATATGAGTGATGG
GGTTTTAGCGACCAATCGGGTTGGAAAAATTACCATGATCAATGATACGGCCCGCAAGCAGCTCAATCTAACCCGAGAAG
AAGCGCTTGAGATGAACATCATGGATTTGATTGACTCGGATGACTATGATTATCGCGATTTGATAACCCAGACTCCAGAG
GTGACTCTCTACCGTCGCAACGAGTACGATGAGTTTATCACCTTGCGGGTTAATTTTGCCCTCAACCGTCGGGAGAGTGG
CTTTATTTCTGGTCTGGTTGCTGTCTTGCACGATACCACTGAGCAGGAGAAGGAAGAGCGAGAGCGTCGTCTCTTTGTCT
CTACCGTCAGCCATGAATTGCGGACCCCCTTGACCTCAGTCAAGTCCTACTTGGAGGCCCTCAATGAAGGGGCCCTCAAT
GAGGATGTGGCCCCCAGCTTTATTCAAGTCTCGTTAGATGAAACCAACCGCATGATGCGGATGATTTCTGATCTCTTACA
ATTGTCGCGAATTGATAATGATACCAGCCACTTAGAAGTTGAAATGACCAACTTCACGGCCTTTATCACGGTTATTCTCA
ATCGTTTCGACCAGATTAAGAGCCAGCAGGACTCCGACAAGGACTATGAAATCGTCCGTAATTATCCCCTCAATCCAATC
TGGGTTGAAATTGATACCGATAAGATGACCCAGGTTTTGGATAATATTCTCAATAATGCCATCAAGTATTCACCTGATGG
TGGCGAGATTACTGTCTCAATGACGACGACCGATACCCAGTTGATTATTTCAATCTCTGACCAAGGTCTGGGTATCCCTA
AGAAGGACCTGCCGATGATTTTCGACCGTTTCTATCGGGTTGATAAGGCCCGCAGTCGGGCTCAAGGCGGTACTGGTTTA
GGCTTGGCCATTGCTAAGGAAATTATAAAGCAGCATCATGGTTTTATTTGGGCTAAGAGTGAATATGGTAAGGGCTCAAC
CTTCACCATTGTCCTCCCTTACGACAAGGAGCCTGACGACTTTGATGATGAATGGGAGGAAGAAGAGTCAGTCAATGACT
AA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(97-161)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.638

91.391

0.682
  micB Streptococcus pneumoniae Cp1015

69.267

93.377

0.647

Multiple sequence alignment