Detailed information NTG1139336

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: DQM75_RS04865
• Genome accession: NZ_LS483380
• Coordinates: 1019326..1020063 (+)
• Length: 245 a.a.
• NCBI ID: WP_111692437.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC11824
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1014326..1025063

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM75_RS04835 (NCTC11824_00970)	-	1014783..1015688 (-)	906	WP_043025804.1	diacylglycerol/lipid kinase family protein	-
DQM75_RS04840 (NCTC11824_00971)	trhA	1015798..1016448 (-)	651	WP_012515586.1	PAQR family membrane homeostasis protein TrhA	-
DQM75_RS04845 (NCTC11824_00972)	-	1016432..1016887 (-)	456	WP_012515587.1	DUF1836 domain-containing protein	-
DQM75_RS04850 (NCTC11824_00973)	-	1017148..1017903 (+)	756	WP_043030786.1	class I SAM-dependent methyltransferase	-
DQM75_RS04855 (NCTC11824_00974)	-	1017931..1018269 (+)	339	WP_014622843.1	cupin domain-containing protein	-
DQM75_RS04860 (NCTC11824_00975)	-	1018271..1018576 (+)	306	WP_111692436.1	AraC family ligand binding domain-containing protein	-
DQM75_RS04865 (NCTC11824_00976)	comE/blpR	1019326..1020063 (+)	738	WP_111692437.1	response regulator transcription factor	Regulator
DQM75_RS04870 (NCTC11824_00977)	-	1020433..1020633 (+)	201	WP_042670621.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
DQM75_RS04875 (NCTC11824_00978)	-	1020700..1021554 (+)	855	WP_111692438.1	ABC transporter ATP-binding protein	-
DQM75_RS10060 (NCTC11824_00979)	-	1021560..1022183 (+)	624	WP_337660730.1	hypothetical protein	-
DQM75_RS10065 (NCTC11824_00980)	-	1022195..1022713 (+)	519	WP_337660731.1	hypothetical protein	-
DQM75_RS04885 (NCTC11824_00981)	-	1022975..1023205 (+)	231	WP_111692439.1	Blp family class II bacteriocin	-
DQM75_RS04895 (NCTC11824_00982)	-	1023998..1024678 (+)	681	WP_228269169.1	thioredoxin family protein	-
DQM75_RS10070	-	1024719..1024850 (+)	132	WP_228269170.1	LPXTG cell wall anchor domain-containing protein	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28904.32 Da
• Isoelectric Point: 7.8796

>NTDB_id=1139336 DQM75_RS04865 WP_111692437.1 1019326..1020063(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPHQLLANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHKLILYSQNERIEFYGFLSEVLKQDPRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKMKALEAS
IKALH

Nucleotide

• Length: 738 bp

>NTDB_id=1139336 DQM75_RS04865 WP_111692437.1 1019326..1020063(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAACAGTTTAGGCTTGAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACGTGTGATCGTTTTGAAGTTTATGGAAAGCCCCATCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATAGTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATTAGAAAGCGTGAC
CCTTACGCTCTCATTGTTTTTGTCACGACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATCGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGTAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATTGAGACCTCTAGTACTCCTCACAAGTTGATTTTGTATTCTCAAAACGAGCGAATAGAATTTTATGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATCCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAATGGGCAGTCTTGCATGGTTTCAAGACTAAAAATGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGCATTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-240)

• Response regulator receiver domain (Response_reg) (18-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.132	98.776	0.535
comE/comE1	Streptococcus equinus JB1	45.041	98.776	0.445
comE/comE2	Streptococcus equinus JB1	36.885	99.592	0.367